Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   LUA78_RS05055 Genome accession   NZ_CP089283
Coordinates   1067331..1068074 (+) Length   247 a.a.
NCBI ID   WP_000660577.1    Uniprot ID   Q9ZN26
Organism   Helicobacter pylori strain J99 derivative isolate D1     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1062331..1073074
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUA78_RS05030 (LUA78_05030) panD 1064479..1064833 (+) 355 Protein_975 aspartate 1-decarboxylase -
  LUA78_RS05035 (LUA78_05035) - 1064836..1065138 (+) 303 WP_000347931.1 YbaB/EbfC family nucleoid-associated protein -
  LUA78_RS05040 (LUA78_05040) - 1065138..1066142 (+) 1005 WP_000468465.1 PDZ domain-containing protein -
  LUA78_RS05045 (LUA78_05045) comB6 1066150..1067205 (+) 1056 WP_000679725.1 P-type conjugative transfer protein TrbL Machinery gene
  LUA78_RS05050 (LUA78_05050) comB7 1067221..1067334 (+) 114 WP_001217877.1 hypothetical protein Machinery gene
  LUA78_RS05055 (LUA78_05055) comB8 1067331..1068074 (+) 744 WP_000660577.1 type IV secretion system protein Machinery gene
  LUA78_RS05060 (LUA78_05060) comB9 1068074..1069060 (+) 987 WP_001878684.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  LUA78_RS05065 (LUA78_05065) comB10 1069053..1070183 (+) 1131 WP_001045766.1 DNA type IV secretion system protein ComB10 Machinery gene
  LUA78_RS05070 (LUA78_05070) - 1070253..1071665 (+) 1413 WP_234618007.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  LUA78_RS05075 (LUA78_05075) gmd 1071706..1072851 (+) 1146 WP_046655973.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28710.95 Da        Isoelectric Point: 8.9891

>NTDB_id=636103 LUA78_RS05055 WP_000660577.1 1067331..1068074(+) (comB8) [Helicobacter pylori strain J99 derivative isolate D1]
MKEKPFNSEQMAFLEELLSHQEKHLESKLSGFSVNDLDMQSVFRLERNRLKIAYRLLGLMSFIALVLAIVLISILPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKAQNSIY
VQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRND

Nucleotide


Download         Length: 744 bp        

>NTDB_id=636103 LUA78_RS05055 WP_000660577.1 1067331..1068074(+) (comB8) [Helicobacter pylori strain J99 derivative isolate D1]
ATGAAAGAAAAGCCGTTCAATAGCGAGCAGATGGCTTTTTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAGAG
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTCGGCTAGAAAGGAACCGCTTGAAAATCGCTT
ACAGGCTTTTAGGTTTGATGAGCTTTATCGCGCTTGTCTTAGCGATCGTTTTAATCAGTATCCTGCCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAATCGCATTGACGATAAATCCCGCT
ATGAACTGGTGCGCTTGCAAAGCAGCTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAGCCCAAAACAGCATCTAT
GTGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
GTCCATTGCGGCTAAACTTTTGAATGAAAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTATTGAGCTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGAATGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9ZN26

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

95.547

100

0.955