Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB6   Type   Machinery gene
Locus tag   LUA78_RS05045 Genome accession   NZ_CP089283
Coordinates   1066150..1067205 (+) Length   351 a.a.
NCBI ID   WP_000679725.1    Uniprot ID   Q9ZN27
Organism   Helicobacter pylori strain J99 derivative isolate D1     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1061150..1072205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUA78_RS05015 (LUA78_05015) - 1061574..1061987 (+) 414 WP_001023005.1 universal stress protein -
  LUA78_RS05020 (LUA78_05020) - 1061989..1062261 (+) 273 WP_000781796.1 ATP-dependent Clp protease adaptor ClpS -
  LUA78_RS05025 (LUA78_05025) - 1062261..1064489 (+) 2229 WP_000357196.1 AAA family ATPase -
  LUA78_RS05030 (LUA78_05030) panD 1064479..1064833 (+) 355 Protein_975 aspartate 1-decarboxylase -
  LUA78_RS05035 (LUA78_05035) - 1064836..1065138 (+) 303 WP_000347931.1 YbaB/EbfC family nucleoid-associated protein -
  LUA78_RS05040 (LUA78_05040) - 1065138..1066142 (+) 1005 WP_000468465.1 PDZ domain-containing protein -
  LUA78_RS05045 (LUA78_05045) comB6 1066150..1067205 (+) 1056 WP_000679725.1 P-type conjugative transfer protein TrbL Machinery gene
  LUA78_RS05050 (LUA78_05050) comB7 1067221..1067334 (+) 114 WP_001217877.1 hypothetical protein Machinery gene
  LUA78_RS05055 (LUA78_05055) comB8 1067331..1068074 (+) 744 WP_000660577.1 type IV secretion system protein Machinery gene
  LUA78_RS05060 (LUA78_05060) comB9 1068074..1069060 (+) 987 WP_001878684.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  LUA78_RS05065 (LUA78_05065) comB10 1069053..1070183 (+) 1131 WP_001045766.1 DNA type IV secretion system protein ComB10 Machinery gene
  LUA78_RS05070 (LUA78_05070) - 1070253..1071665 (+) 1413 WP_234618007.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -

Sequence

Protein


Download         Length: 351 a.a.        Molecular weight: 39746.60 Da        Isoelectric Point: 8.8294

>NTDB_id=636101 LUA78_RS05045 WP_000679725.1 1066150..1067205(+) (comB6) [Helicobacter pylori strain J99 derivative isolate D1]
MKHDAYEIILSWFITPLTAILGRFAEFFLYTLHAQLVFNSAVALAFMLFAYRSLKEQNFFSASALLEALWFVGFFALFNY
ALKNPSRFYELFQNAIFIAPNMITQSLSQSLSNFSNHALSLDFIFNHGFYALSFISDLSHNEMSVWLFLSILQALFLSVL
FAIIILVYLEAHVWCSLGALFLAFGFFKTWRSVVVICLKKCFALGFYKPFLLLVGFLNVSVTKALMDASMQEKQDLSLLL
VVALFLCCVFIIGVPFFINALFRVQNSLKETYKLATNLSANLTQSAFQSLQHATTSPAPSHISSSASQSVSKEKETHSPT
FKVETTQLDVKIPNFKQKKVKKDTIDTKNEI

Nucleotide


Download         Length: 1056 bp        

>NTDB_id=636101 LUA78_RS05045 WP_000679725.1 1066150..1067205(+) (comB6) [Helicobacter pylori strain J99 derivative isolate D1]
ATGAAACATGACGCTTATGAAATCATTCTTTCTTGGTTTATCACGCCTCTCACAGCGATTTTAGGGCGTTTCGCTGAATT
TTTCCTCTACACCTTGCATGCGCAATTGGTGTTTAATAGCGCGGTCGCTTTGGCGTTCATGCTCTTTGCTTACAGGAGTT
TGAAAGAACAGAATTTTTTCAGTGCTAGCGCGCTTTTAGAAGCGTTATGGTTTGTGGGGTTTTTTGCGCTGTTTAACTAC
GCTTTGAAAAATCCTTCGCGCTTTTATGAATTGTTTCAAAACGCTATTTTTATTGCGCCTAACATGATCACTCAAAGCCT
TTCTCAAAGCTTGAGTAACTTTTCTAACCACGCGCTTTCTTTAGATTTTATTTTTAATCATGGTTTTTATGCCCTTAGCT
TCATTAGCGATTTGAGCCATAATGAAATGTCCGTGTGGCTTTTTTTAAGCATTTTGCAAGCGCTTTTTTTGAGCGTGCTG
TTTGCGATCATCATTTTAGTGTATTTGGAAGCGCATGTGTGGTGCTCTTTAGGGGCACTGTTTTTAGCGTTTGGGTTTTT
CAAAACCTGGAGGAGCGTTGTGGTTATATGCCTTAAAAAATGCTTCGCTCTTGGGTTTTACAAGCCTTTTTTGTTGTTAG
TGGGGTTTTTGAATGTGTCGGTTACTAAGGCGTTAATGGACGCTAGCATGCAAGAAAAACAAGACTTAAGCCTTTTATTG
GTGGTGGCGTTATTTTTGTGTTGCGTTTTTATCATCGGTGTGCCTTTTTTCATCAACGCTTTGTTTAGGGTGCAAAACAG
CCTTAAAGAAACTTACAAACTCGCCACCAATTTGAGCGCTAACCTCACTCAAAGCGCTTTCCAATCTTTACAGCATGCCA
CGACCTCGCCCGCTCCTTCTCATATTTCCTCTTCTGCAAGTCAAAGCGTTTCTAAAGAAAAGGAAACGCATTCCCCCACA
TTCAAGGTAGAAACCACTCAATTAGATGTAAAAATCCCAAATTTCAAGCAAAAAAAGGTTAAAAAGGATACAATAGATAC
AAAAAATGAAATTTAA

Domains

Predicted by InterproScan.

TrbL/VirB6 plasmid conjugal transfer protein (TrbL)

(44-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9ZN27

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB6 Helicobacter pylori 26695

92.023

100

0.92