Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   LTK21_RS11460 Genome accession   NZ_CP089161
Coordinates   2362759..2363445 (-) Length   228 a.a.
NCBI ID   WP_232043686.1    Uniprot ID   -
Organism   Staphylococcus aureus strain UNC_SaCF13     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2357759..2368445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LTK21_RS11440 (LTK21_11440) rpsT 2358673..2358924 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  LTK21_RS11445 (LTK21_11445) holA 2358969..2359943 (-) 975 WP_001282563.1 DNA polymerase III subunit delta -
  LTK21_RS11450 (LTK21_11450) comEC 2360000..2362201 (-) 2202 WP_001557362.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LTK21_RS11455 (LTK21_11455) - 2362206..2362667 (-) 462 WP_000439693.1 ComE operon protein 2 -
  LTK21_RS11460 (LTK21_11460) comEA 2362759..2363445 (-) 687 WP_232043686.1 ComEA family DNA-binding protein Machinery gene
  LTK21_RS11465 (LTK21_11465) - 2363485..2364201 (-) 717 WP_000084830.1 class I SAM-dependent methyltransferase -
  LTK21_RS11470 (LTK21_11470) rsfS 2364204..2364557 (-) 354 WP_001088020.1 ribosome silencing factor -
  LTK21_RS11475 (LTK21_11475) yqeK 2364558..2365142 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  LTK21_RS11480 (LTK21_11480) nadD 2365132..2365701 (-) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  LTK21_RS11485 (LTK21_11485) yhbY 2365704..2365994 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  LTK21_RS11490 (LTK21_11490) aroE 2365998..2366804 (-) 807 WP_000666757.1 shikimate dehydrogenase -
  LTK21_RS11495 (LTK21_11495) yqeH 2366818..2367918 (-) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25874.61 Da        Isoelectric Point: 9.6751

>NTDB_id=635540 LTK21_RS11460 WP_232043686.1 2362759..2363445(-) (comEA) [Staphylococcus aureus strain UNC_SaCF13]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVAGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=635540 LTK21_RS11460 WP_232043686.1 2362759..2363445(-) (comEA) [Staphylococcus aureus strain UNC_SaCF13]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTGCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

99.561

100

0.996
  comEA Staphylococcus aureus MW2

96.93

100

0.969