Detailed information NTG0635025

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: N2X48_RS09325
• Genome accession: NZ_CP104913
• Coordinates: 1954815..1956095 (+)
• Length: 426 a.a.
• NCBI ID: WP_003087924.1
• Uniprot ID: Q02KU5
• Organism: Pseudomonas aeruginosa strain PA-AUTBAM
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1949815..1961095

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N2X48_RS09305 (N2X48_09305)	parS	1950439..1951725 (-)	1287	WP_003113589.1	sensor histidine kinase ParS	-
N2X48_RS09310 (N2X48_09310)	parR	1951726..1952433 (-)	708	WP_003098126.1	response regulator transcription factor ParR	-
N2X48_RS09315 (N2X48_09315)	tig	1952665..1953975 (+)	1311	WP_003087920.1	trigger factor	-
N2X48_RS09320 (N2X48_09320)	clpP	1954069..1954710 (+)	642	WP_003098129.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
N2X48_RS09325 (N2X48_09325)	clpX	1954815..1956095 (+)	1281	WP_003087924.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
N2X48_RS09330 (N2X48_09330)	lon	1956227..1958623 (+)	2397	WP_003087926.1	endopeptidase La	-
N2X48_RS09335 (N2X48_09335)	hupB	1958759..1959031 (+)	273	WP_003087931.1	nucleoid-associated protein HU-beta	-

Sequence

Protein

• Length: 426 a.a.
• Molecular weight: 46991.78 Da
• Isoelectric Point: 4.8347

>NTDB_id=635025 N2X48_RS09325 WP_003087924.1 1954815..1956095(+) (clpX) [Pseudomonas aeruginosa strain PA-AUTBAM]
MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSGHKLPAPKEIRTILDQYVI
GQERAKKVLAVAVYNHYKRLNQRDKKDDIELGKSNILMIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVD
TRNILFICGGAFAGLERVIQNRSARGGIGFNAEVRSQEMGKKVGEAFKEVEPEDLVKFGLIPEFVGRLPVIATLDELDEA
ALMQILTEPKNALTKQYAKLFEMEGVDLEFRPDALKAVARKALERKTGARGLRSILEGILLDTMYEIPSQQDVSKVVIDE
SVIDGSSQPLMIYENSEKPAKAAPEA

Nucleotide

• Length: 1281 bp

>NTDB_id=635025 N2X48_RS09325 WP_003087924.1 1954815..1956095(+) (clpX) [Pseudomonas aeruginosa strain PA-AUTBAM]
ATGACTGATACCCGCAACGGCGAGGACAACGGCAAGCTGCTGTATTGCTCCTTCTGCGGCAAGAGCCAGCACGAAGTGCG
CAAGTTGATTGCCGGCCCCTCGGTCTTTATCTGCGACGAGTGTGTCGACCTGTGCAATGACATCATCCGCGAGGAGGTGC
AGGAAGCGCAGGCGGAAAGTAGTGGGCACAAACTTCCGGCGCCGAAAGAGATCCGCACCATCCTCGATCAGTACGTGATC
GGGCAGGAGCGGGCCAAGAAGGTTCTGGCGGTAGCGGTATACAACCACTACAAGCGCCTCAACCAGCGTGACAAGAAGGA
CGATATCGAGCTCGGCAAGAGCAACATTCTGATGATCGGCCCAACCGGCTCGGGCAAGACCCTGCTGGCCGAGACCCTCG
CACGTCTGCTGAACGTGCCGTTCACCATCGCCGATGCGACCACGCTGACGGAAGCGGGCTACGTGGGCGAGGATGTCGAG
AACATCATCCAGAAACTCTTGCAGAAGTGCGATTACGATGTGGAGAAGGCCCAGATGGGCATCGTCTACATCGACGAGAT
CGACAAGATTTCCCGGAAATCGGACAACCCCTCCATCACTCGCGACGTCTCCGGCGAGGGTGTGCAGCAGGCCCTGCTGA
AGCTCATCGAGGGTACCGTTGCCTCGGTACCGCCGCAGGGCGGTCGCAAGCATCCGCAGCAGGAGTTCCTGCAGGTCGAT
ACGCGCAACATCCTGTTCATCTGCGGCGGCGCTTTCGCCGGTCTGGAGCGGGTCATCCAGAACCGTTCCGCGCGCGGCGG
CATCGGTTTCAATGCCGAAGTGCGCAGTCAGGAGATGGGCAAGAAGGTCGGCGAGGCGTTCAAGGAAGTCGAACCGGAAG
ATCTCGTCAAGTTCGGTCTTATTCCCGAGTTTGTAGGGCGTTTGCCGGTGATCGCGACTCTTGATGAGCTCGACGAGGCT
GCGCTCATGCAGATCCTGACCGAGCCGAAGAACGCTCTCACCAAGCAGTACGCCAAGCTGTTCGAAATGGAAGGCGTCGA
TCTCGAATTCCGTCCGGACGCACTCAAGGCGGTTGCCCGCAAGGCGCTCGAACGCAAGACCGGTGCACGTGGCTTGCGTT
CAATTCTCGAAGGTATCCTTCTCGATACCATGTACGAGATTCCCTCCCAGCAGGATGTCAGCAAGGTGGTCATCGATGAG
AGTGTCATCGATGGCTCGTCGCAACCCCTGATGATCTACGAGAACAGCGAAAAGCCAGCCAAGGCTGCGCCTGAGGCATG
A

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (14-51)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (113-311)

3D structure

• AlphaFold DB: Q02KU5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	60.934	95.54	0.582
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.198	94.836	0.523