Detailed information NTG0634736

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: LSO59_RS06770
• Genome accession: NZ_CP089038
• Coordinates: 1452647..1453180 (+)
• Length: 177 a.a.
• NCBI ID: WP_004988651.1
• Uniprot ID: A0AA46P7Y1
• Organism: Acinetobacter ursingii strain RIVM_C011601
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1450224..1462654	1452647..1453180	within	0

Gene organization within MGE regions

Location: 1450224..1462654

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LSO59_RS06765 (LSO59_06750)	-	1451356..1452642 (+)	1287	WP_263505721.1	pilus assembly protein	-
LSO59_RS06770 (LSO59_06755)	comE	1452647..1453180 (+)	534	WP_004988651.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
LSO59_RS06775 (LSO59_06760)	pilE	1453174..1453629 (+)	456	WP_004988647.1	type IV pilin protein	Machinery gene
LSO59_RS19785	-	1454009..1454140 (+)	132	Protein_1314	IS3 family transposase	-
LSO59_RS06780 (LSO59_06765)	tnpA	1454328..1454756 (+)	429	WP_004985693.1	IS66-like element accessory protein TnpA	-
LSO59_RS06785 (LSO59_06770)	tnpB	1454729..1455088 (+)	360	WP_228136324.1	IS66 family insertion sequence element accessory protein TnpB	-
LSO59_RS06790 (LSO59_06775)	tnpC	1455163..1456770 (+)	1608	WP_004985690.1	IS66 family transposase	-
LSO59_RS06795 (LSO59_06780)	-	1457029..1457301 (-)	273	WP_263505722.1	type II toxin-antitoxin system RelE/ParE family toxin	-
LSO59_RS06800 (LSO59_06785)	-	1457306..1457527 (-)	222	WP_263505723.1	ParD-like family protein	-
LSO59_RS06805 (LSO59_06790)	-	1457780..1458343 (-)	564	WP_263505724.1	LysM peptidoglycan-binding domain-containing protein	-
LSO59_RS06810 (LSO59_06795)	-	1458428..1458658 (+)	231	WP_263505743.1	helix-turn-helix domain-containing protein	-
LSO59_RS06815 (LSO59_06800)	-	1458963..1459139 (-)	177	WP_263505725.1	hypothetical protein	-
LSO59_RS06820 (LSO59_06805)	-	1459494..1460684 (-)	1191	WP_263505726.1	hypothetical protein	-
LSO59_RS06825 (LSO59_06810)	-	1460756..1461313 (-)	558	WP_263505727.1	hypothetical protein	-
LSO59_RS19790	-	1461427..1461540 (-)	114	Protein_1325	transcriptional regulator	-

Sequence

Protein

• Length: 177 a.a.
• Molecular weight: 19542.16 Da
• Isoelectric Point: 9.2551

>NTDB_id=634736 LSO59_RS06770 WP_004988651.1 1452647..1453180(+) (comE) [Acinetobacter ursingii strain RIVM_C011601]
MKKETGKIRSHHGYGFTLIELMVTVAIVAIFAAIAFPSYQAYTRKAYAAQTQQEIEKLAEQLERHKARNFNYKGFDASFL
YKDASGVLISNFNNNKQELSLPVDGSSTKYILSIVDQTEGNPLLINSTSLGQGWAIKALSTDDKNDSFLKTSNGIQCKNK
TKANITFSGCGVGSEIW

Nucleotide

• Length: 534 bp

>NTDB_id=634736 LSO59_RS06770 WP_004988651.1 1452647..1453180(+) (comE) [Acinetobacter ursingii strain RIVM_C011601]
ATGAAAAAAGAAACTGGGAAAATACGCTCTCACCACGGCTATGGTTTTACTTTAATTGAGCTGATGGTAACAGTTGCAAT
TGTCGCGATTTTTGCTGCAATTGCATTCCCAAGTTATCAAGCTTATACAAGAAAAGCTTATGCTGCACAGACTCAACAGG
AAATTGAAAAACTGGCTGAGCAATTAGAACGACACAAAGCCCGTAACTTTAATTATAAAGGCTTTGATGCAAGTTTTTTG
TATAAAGATGCAAGTGGTGTTTTAATTTCAAATTTTAATAACAATAAACAAGAGCTTAGTCTTCCAGTGGATGGCTCTTC
TACGAAATACATACTTTCTATTGTAGATCAAACGGAGGGGAATCCTCTGTTGATTAACTCAACATCTTTGGGGCAGGGCT
GGGCAATTAAGGCATTAAGCACTGATGATAAGAATGATAGTTTTTTAAAAACTAGCAACGGTATTCAATGTAAAAATAAA
ACCAAAGCAAATATCACTTTTTCGGGATGTGGTGTGGGGAGCGAGATATGGTAG

Domains

Predicted by InterproScan.

• Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS) (37-114)

• Prokaryotic N-terminal methylation motif (N_methyl) (15-36)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Acinetobacter baylyi ADP1	59.88	94.35	0.565
pilY2	Acinetobacter baumannii D1279779	40.936	96.61	0.395