Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   N7761_RS10120 Genome accession   NZ_CP104882
Coordinates   2055800..2057629 (+) Length   609 a.a.
NCBI ID   WP_005567177.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain IDHaas10a     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2050800..2062629
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N7761_RS10100 (N7761_10100) msbA 2051944..2053692 (+) 1749 WP_005567181.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  N7761_RS10105 (N7761_10105) lpxK 2053711..2054685 (+) 975 WP_005589925.1 tetraacyldisaccharide 4'-kinase -
  N7761_RS10110 (N7761_10110) - 2054707..2054886 (+) 180 WP_005567179.1 Trm112 family protein -
  N7761_RS10115 (N7761_10115) kdsB 2054888..2055661 (+) 774 WP_005570275.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  N7761_RS10120 (N7761_10120) uvrC 2055800..2057629 (+) 1830 WP_005567177.1 excinuclease ABC subunit UvrC Machinery gene
  N7761_RS10125 (N7761_10125) - 2058016..2059107 (-) 1092 WP_014167754.1 extracellular solute-binding protein -
  N7761_RS10130 (N7761_10130) - 2059127..2059978 (-) 852 WP_050846361.1 ABC transporter permease -
  N7761_RS10135 (N7761_10135) - 2059975..2060844 (-) 870 WP_005567173.1 ABC transporter permease -
  N7761_RS10140 (N7761_10140) - 2060841..2061847 (-) 1007 Protein_1951 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 609 a.a.        Molecular weight: 69083.11 Da        Isoelectric Point: 9.5140

>NTDB_id=634663 N7761_RS10120 WP_005567177.1 2055800..2057629(+) (uvrC) [Aggregatibacter actinomycetemcomitans strain IDHaas10a]
MTFDAKKFLANVPHLPGVYRMYDDKSTVIYVGKAKDLKKRLSSYFRKQLSSKKTEALVASIQHIETTITTSETEALLLEH
NYIKTYQPRYNVLLRDDKSYPYILLTKETHPRITAYRGSKKIQGEYFGPYPNAGAVRETLSLLQKLFPIRQCENSVYNNR
SRPCLQYQIGRCLAPCVKGYVTDEAYAQQVNFARLFLQGKDQQVLDHLVKQMEQASQQLNFEEAARVRDQIQAVRAVIEK
QFVANDRHDDIDIIAITYQLGVACVQVLFIRQGKILGNRSYFPKVPSNTNLAELTETFVGQFYLQAHQGRTIPNTIIVDQ
KLDEKVDLETLLSDQAGRKVSIQDHAKGDKSKYLQLAQMNAKAALVTKLKQSTLQHDRYVALQELLGIAAIKRMECFDIS
HTMGEQTTASCVVFNQDGPLKSDYRRFNISGITKGDDYAAMEQALLKRYDKDLEDDKIPDIIFIDGGKGQLNRALQVFEN
LNVKWNKNQPHLIGVAKGVDRRAGLETLILSKWDKELHLPADSLALHLIQHIRDESHNHAISGHRKKRQQHFTQSGLESI
EGVGAKRRQALLKYLGGLQGVKNATLDEIASVPGISKALAEKIFETLQH

Nucleotide


Download         Length: 1830 bp        

>NTDB_id=634663 N7761_RS10120 WP_005567177.1 2055800..2057629(+) (uvrC) [Aggregatibacter actinomycetemcomitans strain IDHaas10a]
ATGACTTTCGACGCCAAAAAATTCCTCGCCAACGTACCGCACTTACCGGGCGTTTATCGTATGTATGACGATAAAAGCAC
GGTGATTTATGTGGGCAAGGCGAAAGATCTGAAAAAACGCTTATCCAGTTATTTTCGCAAGCAGTTAAGCAGCAAAAAAA
CGGAAGCATTGGTGGCGTCGATTCAGCATATCGAAACCACCATTACCACATCGGAAACCGAAGCCCTGCTCCTAGAGCAC
AATTACATCAAAACCTACCAGCCGCGCTATAACGTGCTGTTGCGCGATGATAAATCTTATCCGTACATTTTATTAACCAA
AGAAACCCACCCGCGTATTACCGCTTATCGCGGTTCGAAAAAAATCCAAGGGGAATATTTCGGTCCTTATCCGAATGCCG
GTGCAGTGCGCGAAACCCTGTCTTTATTACAAAAACTGTTCCCCATTCGGCAGTGTGAAAACTCCGTGTATAACAACCGT
TCGCGCCCCTGTTTGCAGTATCAAATCGGGCGTTGTCTGGCGCCTTGCGTAAAGGGCTATGTGACCGATGAAGCCTATGC
GCAGCAGGTCAATTTCGCCCGCTTGTTTTTACAAGGAAAAGATCAACAGGTGCTGGATCATTTGGTGAAGCAAATGGAAC
AGGCAAGTCAGCAACTGAATTTTGAAGAAGCGGCACGCGTTCGTGATCAAATTCAGGCAGTGCGGGCAGTAATTGAAAAA
CAATTTGTCGCCAACGATCGCCATGACGACATTGATATTATCGCCATCACCTATCAACTCGGCGTGGCCTGCGTGCAGGT
TTTGTTTATTCGTCAAGGTAAGATTTTGGGCAATCGCAGCTATTTTCCTAAAGTCCCGAGCAATACCAATCTGGCAGAAC
TCACGGAAACCTTTGTGGGGCAATTTTATTTGCAGGCGCACCAAGGCAGAACCATTCCGAACACCATTATCGTGGATCAA
AAACTGGACGAAAAAGTCGATTTGGAAACTTTACTCAGCGACCAAGCGGGACGCAAAGTCAGCATTCAGGATCATGCCAA
AGGCGATAAAAGCAAATATTTGCAACTGGCACAAATGAACGCCAAAGCGGCGTTAGTCACCAAATTAAAACAATCCACAT
TACAGCACGATCGCTACGTCGCACTGCAGGAATTACTCGGCATCGCTGCCATCAAACGCATGGAATGTTTCGACATCAGC
CACACCATGGGCGAACAAACCACCGCCTCCTGCGTGGTTTTCAACCAAGACGGACCGCTGAAATCCGATTACCGCCGTTT
CAACATCAGCGGCATCACCAAAGGCGACGATTACGCCGCCATGGAACAAGCCCTGTTAAAACGCTACGACAAAGATCTGG
AAGACGACAAAATTCCCGACATTATTTTTATCGACGGCGGCAAGGGACAACTCAACCGCGCGTTGCAGGTGTTCGAAAAC
CTTAATGTAAAATGGAACAAAAACCAACCGCACTTAATCGGTGTTGCCAAAGGCGTGGATCGTCGTGCCGGTTTGGAAAC
CTTGATTTTGAGCAAATGGGACAAAGAATTGCATTTACCGGCGGACAGCCTTGCGCTTCACTTGATCCAGCATATCCGCG
ACGAAAGCCACAATCACGCCATTAGCGGACACCGCAAAAAACGCCAACAACATTTCACCCAAAGTGGCTTGGAAAGCATT
GAAGGCGTCGGCGCCAAACGCCGCCAAGCCCTGCTCAAATACCTCGGCGGCTTGCAAGGCGTCAAAAATGCCACCCTCGA
CGAAATCGCCTCCGTCCCCGGCATATCAAAAGCCCTGGCAGAAAAGATTTTTGAGACCTTGCAGCATTAG

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(16-91)

UvrB/uvrC motif (UVR)

(203-236)

Helix-hairpin-helix domain (HHH_5)

(557-608)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-541)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.52

100

0.378
  uvrC Streptococcus pneumoniae R6

37.194

100

0.374
  uvrC Streptococcus pneumoniae D39

37.194

100

0.374