Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N7217_RS10125 Genome accession   NZ_CP104843
Coordinates   2116812..2117468 (+) Length   218 a.a.
NCBI ID   WP_022645829.1    Uniprot ID   -
Organism   Escherichia coli strain DFL.5     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2111812..2122468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N7217_RS10095 (N7217_10095) dcyD 2112692..2113678 (+) 987 WP_001128235.1 D-cysteine desulfhydrase -
  N7217_RS10100 (N7217_10100) tcyL 2113693..2114361 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  N7217_RS10105 (N7217_10105) tcyN 2114358..2115110 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N7217_RS10110 (N7217_10110) sdiA 2115340..2116062 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  N7217_RS10115 (N7217_10115) yecF 2116129..2116353 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  N7217_RS10120 (N7217_10120) yecU 2116340..2116516 (-) 177 WP_001307856.1 protein YecU -
  N7217_RS10125 (N7217_10125) letA 2116812..2117468 (+) 657 WP_022645829.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N7217_RS10130 (N7217_10130) uvrC 2117465..2119294 (+) 1830 Protein_1987 excinuclease ABC subunit UvrC -
  N7217_RS10135 (N7217_10135) pgsA 2119354..2119902 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N7217_RS10155 (N7217_10155) - 2120600..2121241 (-) 642 Protein_1989 hypothetical protein -
  N7217_RS10160 (N7217_10160) - 2121314..2122402 (+) 1089 Protein_1990 IS3 family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23938.73 Da        Isoelectric Point: 6.9612

>NTDB_id=633419 N7217_RS10125 WP_022645829.1 2116812..2117468(+) (letA) [Escherichia coli strain DFL.5]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIAYDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=633419 N7217_RS10125 WP_022645829.1 2116812..2117468(+) (letA) [Escherichia coli strain DFL.5]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTATGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482