Detailed information NTG0063340

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: STP1_RS02130
• Genome accession: NC_022737
• Coordinates: 464913..465956 (-)
• Length: 347 a.a.
• NCBI ID: WP_002452288.1
• Uniprot ID: A0A2T4Q1J8
• Organism: Staphylococcus pasteuri SP1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 459913..470956

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STP1_RS02100 (STP1_0398)	-	460413..461654 (-)	1242	WP_023373108.1	aminopeptidase	-
STP1_RS02105 (STP1_0399)	-	461667..461870 (-)	204	WP_041613607.1	DUF1128 domain-containing protein	-
STP1_RS02110 (STP1_0400)	-	462017..462481 (+)	465	WP_023373112.1	low molecular weight protein-tyrosine-phosphatase	-
STP1_RS02115 (STP1_0401)	-	462488..462772 (+)	285	WP_002466132.1	YtxH domain-containing protein	-
STP1_RS02120 (STP1_0402)	-	463000..464235 (+)	1236	WP_023373114.1	YihY/virulence factor BrkB family protein	-
STP1_RS02125 (STP1_0403)	vraR	464294..464923 (-)	630	WP_002466112.1	two-component system response regulator VraR	Regulator
STP1_RS02130 (STP1_0404)	vraS	464913..465956 (-)	1044	WP_002452288.1	sensor histidine kinase	Regulator
STP1_RS02135 (STP1_0405)	liaF	465953..466654 (-)	702	WP_023373116.1	cell wall-active antibiotics response protein LiaF	-
STP1_RS02140 (STP1_0406)	-	466669..467055 (-)	387	WP_023373118.1	DUF2543 family protein	-
STP1_RS02145 (STP1_0407)	map	467199..467954 (-)	756	WP_023373120.1	type I methionyl aminopeptidase	-
STP1_RS02150 (STP1_0408)	-	468121..469107 (+)	987	WP_023373122.1	aromatic acid exporter family protein	-
STP1_RS02155 (STP1_0409)	-	469174..469899 (-)	726	WP_023373124.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40101.60 Da
• Isoelectric Point: 6.2449

>NTDB_id=63340 STP1_RS02130 WP_002452288.1 464913..465956(-) (vraS) [Staphylococcus pasteuri SP1]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMIQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=63340 STP1_RS02130 WP_002452288.1 464913..465956(-) (vraS) [Staphylococcus pasteuri SP1]
ATGAACCACTATATAAGAGCTATTGGGTCTATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGCATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTAGGGTCAGTTTTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGACCAAAATATTGAATTGTATAGCGAGACGTTGGAAAT
ATATCACACACTCGTTCCATTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTATA
ATATGAATGATGTTAAAGTTAAAAAAATTATTGAAGATGAGCGACAACGCTTAGCTAGGGAATTGCATGATTCTGTAAGC
CAACAATTATTTGCAGCAAGTATGATGTTATCAGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTTCTTGAAAAAATGATTCAAGATTCACAACTTGAAATGAGAGCATTGTTACTTCATTTAAGACCACTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTCCATGAAATC
CAAGAATTTAAAGTACCAAAAGGAATAGAAGATCATTTATTCAGAATCACACAAGAAGCAATTTCAAATACTTTGAGACA
TTCTAATGGTACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTACTTTTACGTATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGCTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCCACA
TTCCATATCGTATCATTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A2T4Q1J8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.524	100	0.945