Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N6H17_RS10930 Genome accession   NZ_CP104788
Coordinates   2181477..2182133 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain SHP24     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2176477..2187133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N6H17_RS10900 (N6H17_10905) - 2177607..2178347 (+) 741 Protein_2145 hypothetical protein -
  N6H17_RS10920 (N6H17_10925) pgsA 2179043..2179591 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N6H17_RS10925 (N6H17_10930) uvrC 2179648..2181480 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  N6H17_RS10930 (N6H17_10935) letA 2181477..2182133 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N6H17_RS27235 - 2182275..2182391 (+) 117 WP_001302039.1 hypothetical protein -
  N6H17_RS10935 (N6H17_10940) yecU 2182429..2182605 (+) 177 WP_000590347.1 protein YecU -
  N6H17_RS10940 (N6H17_10945) yecF 2182592..2182816 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  N6H17_RS10945 (N6H17_10950) sdiA 2182884..2183606 (-) 723 WP_001154287.1 transcriptional regulator SdiA -
  N6H17_RS10950 (N6H17_10955) tcyN 2183836..2184588 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N6H17_RS10955 (N6H17_10960) tcyL 2184585..2185253 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  N6H17_RS10960 (N6H17_10965) dcyD 2185268..2186254 (-) 987 WP_001128213.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=633244 N6H17_RS10930 WP_000611335.1 2181477..2182133(-) (letA) [Escherichia coli strain SHP24]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=633244 N6H17_RS10930 WP_000611335.1 2181477..2182133(-) (letA) [Escherichia coli strain SHP24]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
TAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCTAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486