Detailed information NTG0632995

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LQK05_RS09925
• Genome accession: NZ_CP088157
• Coordinates: 1994001..1995044 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 199
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1989001..2000044

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LQK05_RS09895 (LQK05_09895)	-	1989423..1990679 (-)	1257	WP_217654526.1	aminopeptidase	-
LQK05_RS09900 (LQK05_09900)	-	1990682..1990882 (-)	201	WP_000180460.1	DUF1128 family protein	-
LQK05_RS09905 (LQK05_09905)	-	1991029..1991493 (+)	465	WP_000567539.1	low molecular weight protein-tyrosine-phosphatase	-
LQK05_RS09910 (LQK05_09910)	-	1991500..1991775 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
LQK05_RS09915 (LQK05_09915)	-	1992053..1993270 (+)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
LQK05_RS09920 (LQK05_09920)	vraR	1993382..1994011 (-)	630	WP_000153532.1	two-component system response regulator VraR	Regulator
LQK05_RS09925 (LQK05_09925)	vraS	1994001..1995044 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
LQK05_RS09930 (LQK05_09930)	liaF	1995041..1995742 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
LQK05_RS09935 (LQK05_09935)	-	1995757..1996143 (-)	387	WP_001110179.1	hypothetical protein	-
LQK05_RS09940 (LQK05_09940)	map	1996360..1997118 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
LQK05_RS09945 (LQK05_09945)	-	1997534..1998520 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
LQK05_RS09950 (LQK05_09950)	-	1998951..1999364 (-)	414	WP_025175030.1	hypothetical protein	-
LQK05_RS09955 (LQK05_09955)	-	1999393..1999503 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=632995 LQK05_RS09925 WP_001017131.1 1994001..1995044(-) (vraS) [Staphylococcus aureus strain 199]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=632995 LQK05_RS09925 WP_001017131.1 1994001..1995044(-) (vraS) [Staphylococcus aureus strain 199]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTGAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1