Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N5932_RS27030 Genome accession   NZ_CP104645
Coordinates   5410515..5411171 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain PNUSAE019785     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 5405515..5416171
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N5932_RS26990 (N5932_26990) - 5406484..5406651 (-) 168 Protein_5297 hypothetical protein -
  N5932_RS26995 (N5932_26995) - 5406593..5406787 (-) 195 WP_115801851.1 hypothetical protein -
  N5932_RS27000 (N5932_27000) - 5406808..5407089 (-) 282 WP_001303543.1 hypothetical protein -
  N5932_RS27020 (N5932_27020) pgsA 5408081..5408629 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N5932_RS27025 (N5932_27025) uvrC 5408686..5410518 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  N5932_RS27030 (N5932_27030) letA 5410515..5411171 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N5932_RS28100 - 5411313..5411429 (+) 117 WP_001302039.1 hypothetical protein -
  N5932_RS27035 (N5932_27035) yecU 5411467..5411643 (+) 177 WP_001302050.1 protein YecU -
  N5932_RS27040 (N5932_27040) yecF 5411630..5411854 (+) 225 WP_000106478.1 DUF2594 family protein YecF -
  N5932_RS27045 (N5932_27045) sdiA 5411922..5412644 (-) 723 WP_001154288.1 transcriptional regulator SdiA -
  N5932_RS27050 (N5932_27050) tcyN 5412874..5413626 (-) 753 WP_001273005.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N5932_RS27055 (N5932_27055) tcyL 5413623..5414291 (-) 669 WP_001158226.1 cystine ABC transporter permease -
  N5932_RS27060 (N5932_27060) dcyD 5414306..5415292 (-) 987 WP_001128225.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=632090 N5932_RS27030 WP_000611328.1 5410515..5411171(-) (letA) [Escherichia coli strain PNUSAE019785]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=632090 N5932_RS27030 WP_000611328.1 5410515..5411171(-) (letA) [Escherichia coli strain PNUSAE019785]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482