Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N5855_RS08105 Genome accession   NZ_CP104629
Coordinates   1709479..1710135 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain AHM21C2872I     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1704479..1715135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N5855_RS08075 (N5855_08060) yecA 1705730..1706395 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  N5855_RS08095 (N5855_08080) pgsA 1707045..1707593 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N5855_RS08100 (N5855_08085) uvrC 1707650..1709482 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  N5855_RS08105 (N5855_08090) letA 1709479..1710135 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N5855_RS26600 - 1710277..1710393 (+) 117 WP_001302039.1 hypothetical protein -
  N5855_RS08110 (N5855_08095) yecU 1710431..1710607 (+) 177 WP_000590344.1 protein YecU -
  N5855_RS08115 (N5855_08100) yecF 1710594..1710818 (+) 225 WP_284657478.1 DUF2594 family protein YecF -
  N5855_RS08120 (N5855_08105) sdiA 1710885..1711607 (-) 723 WP_040234759.1 transcriptional regulator SdiA -
  N5855_RS08125 (N5855_08110) tcyN 1711837..1712589 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N5855_RS08130 (N5855_08115) tcyL 1712586..1713254 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  N5855_RS08135 (N5855_08120) dcyD 1713269..1714255 (-) 987 WP_001128242.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=631874 N5855_RS08105 WP_000611328.1 1709479..1710135(-) (letA) [Escherichia coli strain AHM21C2872I]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=631874 N5855_RS08105 WP_000611328.1 1709479..1710135(-) (letA) [Escherichia coli strain AHM21C2872I]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482