Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N5861_RS12270 Genome accession   NZ_CP104598
Coordinates   2546732..2547388 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain AHM8C160RI     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2541732..2552388
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N5861_RS12240 (N5861_12200) yecA 2542984..2543649 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  N5861_RS12260 (N5861_12220) pgsA 2544298..2544846 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N5861_RS12265 (N5861_12225) uvrC 2544903..2546735 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  N5861_RS12270 (N5861_12230) letA 2546732..2547388 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N5861_RS24960 - 2547530..2547601 (+) 72 Protein_2403 transcriptional regulator -
  N5861_RS12275 (N5861_12235) yecU 2547684..2547860 (+) 177 WP_250308192.1 protein YecU -
  N5861_RS12280 (N5861_12240) yecF 2547847..2548071 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  N5861_RS12285 (N5861_12245) sdiA 2548138..2548860 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  N5861_RS12290 (N5861_12250) tcyN 2549090..2549842 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N5861_RS12295 (N5861_12255) tcyL 2549839..2550507 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  N5861_RS12300 (N5861_12260) dcyD 2550522..2551508 (-) 987 WP_001614601.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=631641 N5861_RS12270 WP_000611335.1 2546732..2547388(-) (letA) [Escherichia coli strain AHM8C160RI]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=631641 N5861_RS12270 WP_000611335.1 2546732..2547388(-) (letA) [Escherichia coli strain AHM8C160RI]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486