Detailed information NTG0631622

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: N5861_RS05130
• Genome accession: NZ_CP104598
• Coordinates: 1074070..1075344 (+)
• Length: 424 a.a.
• NCBI ID: WP_000130305.1
• Uniprot ID: P0A6H2
• Organism: Escherichia coli strain AHM8C160RI
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1069070..1080344

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N5861_RS05110 (N5861_05100)	yajG	1070233..1070811 (-)	579	WP_001295326.1	lipoprotein	-
N5861_RS05115 (N5861_05105)	bolA	1071116..1071433 (+)	318	WP_000973448.1	transcriptional regulator BolA	-
N5861_RS05120 (N5861_05110)	tig	1071777..1073075 (+)	1299	WP_001612516.1	trigger factor	-
N5861_RS05125 (N5861_05115)	clpP	1073321..1073944 (+)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
N5861_RS05130 (N5861_05120)	clpX	1074070..1075344 (+)	1275	WP_000130305.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
N5861_RS05135 (N5861_05125)	lon	1075532..1077886 (+)	2355	WP_001295325.1	endopeptidase La	-
N5861_RS05140 (N5861_05130)	hupB	1078095..1078367 (+)	273	WP_001043542.1	nucleoid-associated protein HU-beta	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46356.01 Da
• Isoelectric Point: 4.9982

>NTDB_id=631622 N5861_RS05130 WP_000130305.1 1074070..1075344(+) (clpX) [Escherichia coli strain AHM8C160RI]
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIDGQSKPLLIYGKPEAQQASGE

Nucleotide

• Length: 1275 bp

>NTDB_id=631622 N5861_RS05130 WP_000130305.1 1074070..1075344(+) (clpX) [Escherichia coli strain AHM8C160RI]
ATGACAGATAAACGCAAAGATGGCTCAGGCAAATTGCTGTATTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGCAA
GCTGATTGCCGGTCCATCCGTGTATATCTGCGACGAATGTGTTGATTTATGTAACGACATCATTCGCGAAGAGATTAAAG
AAGTTGCACCGCATCGTGAACGCAGTGCGCTACCGACGCCGCATGAAATTCGTAACCACCTGGACGATTACGTTATCGGC
CAGGAACAGGCGAAAAAAGTGCTGGCGGTCGCGGTATACAACCATTACAAACGTCTGCGCAACGGCGATACCAGCAATGG
TGTCGAGTTGGGCAAAAGTAACATTCTGCTGATCGGTCCGACTGGTTCCGGTAAAACGCTGCTGGCTGAAACGCTGGCGC
GCCTGCTGGACGTCCCGTTCACCATGGCCGACGCAACCACGCTGACCGAAGCCGGTTATGTGGGCGAAGACGTTGAAAAC
ATCATTCAGAAGCTGTTGCAAAAGTGCGATTACGACGTACAGAAAGCGCAGCGCGGGATTGTCTACATCGATGAAATCGA
CAAGATTTCTCGTAAGTCAGACAACCCGTCTATTACCCGTGACGTTTCCGGTGAAGGCGTACAGCAGGCACTGTTGAAAC
TGATCGAAGGTACGGTAGCTGCTGTTCCACCGCAAGGTGGGCGTAAACATCCGCAGCAGGAATTCTTGCAGGTTGATACC
TCTAAGATCCTGTTTATTTGTGGCGGTGCGTTTGCCGGTCTGGATAAAGTGATTTCCCATCGTGTAGAAACCGGCTCCGG
CATTGGTTTTGGCGCGACGGTAAAAGCGAAGTCCGACAAAGCAAGCGAAGGCGAGCTGCTGGCGCAGGTTGAACCGGAAG
ATCTGATCAAGTTTGGTCTTATCCCTGAGTTTATTGGTCGTCTGCCGGTTGTCGCAACGTTGAATGAACTGAGCGAAGAA
GCTCTGATTCAGATCCTCAAAGAGCCGAAAAACGCCCTGACCAAGCAGTATCAGGCGCTGTTTAATCTGGAAGGCGTGGA
TCTGGAATTCCGTGACGAGGCGCTGGATGCTATCGCTAAGAAAGCGATGGCGCGTAAAACCGGTGCCCGTGGCCTGCGTT
CCATCGTAGAAGCCGCACTGCTCGATACCATGTACGATCTGCCGTCCATGGAAGATGTCGAAAAAGTGGTTATCGACGAG
TCGGTAATTGATGGTCAAAGCAAACCGTTGCTGATTTATGGCAAGCCGGAAGCGCAACAGGCATCTGGTGAATAA

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (112-310)

3D structure

• AlphaFold DB: P0A6H2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.85	94.575	0.566
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.392	96.226	0.533