Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilV/pilI   Type   Regulator
Locus tag   NDL69_RS02680 Genome accession   NZ_CP104548
Coordinates   517815..518429 (+) Length   204 a.a.
NCBI ID   WP_012503479.1    Uniprot ID   B4RKG4
Organism   Neisseria gonorrhoeae strain 10538     
Function   repress natural transformation; antagonize ComP (predicted from homology)   
Competence regulation

Genomic Context

Location: 512815..523429
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NDL69_RS02655 (NDL69_02650) - 513313..513645 (+) 333 WP_003687908.1 hypothetical protein -
  NDL69_RS02660 (NDL69_02655) - 513975..514484 (+) 510 WP_003687909.1 isoprenylcysteine carboxyl methyltransferase family protein -
  NDL69_RS02665 (NDL69_02660) - 514716..515297 (-) 582 WP_003690895.1 superoxide dismutase -
  NDL69_RS02670 (NDL69_02665) dnaB 515461..516864 (+) 1404 WP_012503477.1 replicative DNA helicase -
  NDL69_RS12060 - 516858..516970 (-) 113 Protein_519 IS5/IS1182 family transposase -
  NDL69_RS02675 (NDL69_02670) pilH 517121..517783 (+) 663 WP_041421240.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  NDL69_RS02680 (NDL69_02675) pilV/pilI 517815..518429 (+) 615 WP_012503479.1 type IV pilus modification protein PilV Regulator
  NDL69_RS02685 (NDL69_02680) pilJ 518426..519385 (+) 960 WP_260247272.1 PilW family protein Machinery gene
  NDL69_RS02690 (NDL69_02685) pilK 519364..519963 (+) 600 WP_260247273.1 pilus assembly protein Machinery gene
  NDL69_RS02695 (NDL69_02690) pilL 519978..520451 (+) 474 WP_012503482.1 PilX family type IV pilin Machinery gene
  NDL69_RS02700 (NDL69_02695) - 520521..520829 (-) 309 WP_003706588.1 AzlD family protein -
  NDL69_RS02705 (NDL69_02700) - 520826..521537 (-) 712 Protein_526 AzlC family ABC transporter permease -
  NDL69_RS02710 (NDL69_02705) dut 521703..522155 (+) 453 WP_003701071.1 dUTP diphosphatase -
  NDL69_RS02715 (NDL69_02710) dapC 522227..523414 (+) 1188 WP_003701073.1 succinyldiaminopimelate transaminase -

Sequence

Protein


Download         Length: 204 a.a.        Molecular weight: 22099.99 Da        Isoelectric Point: 4.9673

>NTDB_id=630801 NDL69_RS02680 WP_012503479.1 517815..518429(+) (pilV/pilI) [Neisseria gonorrhoeae strain 10538]
MKNNDCLRLKNPQSGMALIEVLVAMLVLTIGILALLSVQLRTVASVREAETQTIVSQITQNLMEGMLMNPTIDSDSNKKN
YNLYTGPYTPTPSGGDFKLNNNNLISKKDLAKAQLDRFDYELRNALPDAVAIHYAVCKDSSGGAPTLSGGTFSPNCDNKA
NGDTLIKVLWVNDSAGDSDISRTNLEVSGDNIVYTYQARVGGHE

Nucleotide


Download         Length: 615 bp        

>NTDB_id=630801 NDL69_RS02680 WP_012503479.1 517815..518429(+) (pilV/pilI) [Neisseria gonorrhoeae strain 10538]
ATGAAGAATAATGATTGCTTGCGCCTGAAAAATCCCCAGTCCGGTATGGCGTTGATAGAAGTCTTGGTCGCTATGCTCGT
TCTGACCATCGGTATTTTGGCATTGCTGTCCGTACAGTTGCGGACGGTCGCTTCCGTCAGGGAGGCGGAGACACAAACCA
TCGTCAGCCAAATCACGCAAAACCTGATGGAAGGAATGTTGATGAATCCGACCATTGATTCGGACAGCAACAAGAAAAAC
TATAATCTTTACACGGGGCCGTACACCCCCACTCCCTCTGGCGGCGATTTCAAGCTTAATAATAATAATTTGATAAGTAA
GAAGGATTTGGCAAAAGCCCAGTTGGACAGGTTCGATTATGAATTGAGAAACGCCTTGCCGGATGCGGTAGCTATTCATT
ACGCCGTCTGCAAGGATTCGTCGGGTGGCGCGCCGACATTGTCCGGCGGTACTTTTTCTCCAAATTGCGATAATAAGGCA
AACGGGGATACTTTGATTAAAGTATTGTGGGTAAATGATTCGGCAGGGGATTCGGATATTTCCCGTACGAATCTTGAGGT
GAGCGGCGACAATATCGTATATACCTATCAGGCAAGGGTCGGAGGTCATGAATGA

Domains

Predicted by InterProScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-36)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B4RKG4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilV/pilI Neisseria gonorrhoeae MS11

90.686

100

0.907
  pilV Neisseria meningitidis 8013

84.135

100

0.858