Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   N596_RS09440 Genome accession   NC_022584
Coordinates   1984796..1986094 (+) Length   432 a.a.
NCBI ID   WP_023027745.1    Uniprot ID   -
Organism   Streptococcus ilei     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1979796..1991094
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N596_RS09415 (N596_09685) - 1980312..1980944 (+) 633 WP_042361376.1 response regulator transcription factor -
  N596_RS09420 (N596_09690) - 1980989..1982395 (+) 1407 WP_042361377.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  N596_RS09425 (N596_09695) - 1982392..1982760 (+) 369 WP_023027742.1 S1 RNA-binding domain-containing protein -
  N596_RS09430 (N596_09700) cysK 1983087..1984016 (-) 930 WP_023027743.1 cysteine synthase A -
  N596_RS09435 (N596_09705) - 1984108..1984740 (-) 633 WP_023027744.1 YigZ family protein -
  N596_RS09440 (N596_09710) comFA/cflA 1984796..1986094 (+) 1299 WP_023027745.1 DEAD/DEAH box helicase Machinery gene
  N596_RS09445 (N596_09715) - 1986157..1986762 (+) 606 WP_258025868.1 ComF family protein -
  N596_RS09450 (N596_09720) hpf 1986850..1987395 (+) 546 WP_023022375.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49766.24 Da        Isoelectric Point: 9.5868

>NTDB_id=62993 N596_RS09440 WP_023027745.1 1984796..1986094(+) (comFA/cflA) [Streptococcus ilei]
MKVEDCYGRLFTQEQLEVELLGQAQRLPAMVEEKTGLLCNRCGSQIDKTRWKLQIGSYYCRACIQLGRVRSDQVLYYFPQ
KAFPQEEVLRWQGSLTPFQSRVSQELVQSLTDRKPMMVHAVTGAGKTEMMYQVVAEVIKKGRCVCIATPRIDVCIELYKR
MTKDFSCPISLLHGDSEAYFRTPLVISTTHQLLKFYQAFDLLIIDEVDAFPFVDNPVLYHAVSNAVTKNGKLIYLTATST
KELDKKVKKQEINRVSLPRRFHGNPLVIPRKVWLKDLRKKVEKKQVPVKLLRLIKEQRKTSFPLILFVSEIELGEKLLNL
LRQNFKDEIIELVTSKTENRLELVEKFRNQEITILVSTTILERGVTFPKVDVFVIEANHRLFTKSTLVQIAGRVGRSMER
PTGELLFLAEGTSQEMTQAIKEIKEMNQEAGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=62993 N596_RS09440 WP_023027745.1 1984796..1986094(+) (comFA/cflA) [Streptococcus ilei]
ATGAAAGTTGAAGATTGTTATGGAAGGTTGTTCACCCAAGAACAACTAGAGGTGGAACTGCTTGGACAAGCCCAGCGTCT
GCCAGCTATGGTAGAGGAAAAGACGGGCTTGCTTTGTAATCGTTGCGGAAGCCAGATTGATAAGACTAGATGGAAACTAC
AGATAGGAAGCTACTATTGTAGAGCCTGCATTCAATTAGGAAGAGTTAGGAGCGACCAAGTACTCTATTACTTTCCCCAG
AAAGCCTTTCCGCAGGAAGAAGTCCTAAGATGGCAGGGGAGCCTGACGCCATTTCAAAGTCGGGTTTCTCAAGAGTTGGT
TCAATCCTTAACAGATAGAAAGCCTATGATGGTACACGCAGTTACAGGAGCAGGTAAAACGGAAATGATGTACCAAGTGG
TGGCGGAAGTGATAAAAAAGGGGAGATGTGTTTGCATTGCTACACCAAGGATTGACGTGTGTATTGAATTATATAAGCGA
ATGACAAAGGACTTTTCCTGCCCCATCTCGTTGTTGCACGGTGATTCAGAAGCTTATTTCCGAACGCCTCTCGTCATATC
CACCACACATCAACTACTAAAATTTTATCAAGCTTTTGACCTCCTCATAATCGATGAAGTCGATGCCTTTCCTTTTGTTG
ATAACCCTGTTCTCTACCATGCCGTTTCAAATGCCGTAACCAAGAATGGAAAGCTCATCTATTTGACAGCTACCTCAACA
AAAGAGTTAGATAAAAAGGTCAAAAAACAGGAAATAAACCGCGTTAGCCTACCCAGACGCTTTCACGGAAACCCTCTAGT
AATTCCTAGAAAAGTATGGCTAAAAGATCTACGAAAGAAAGTAGAAAAGAAGCAAGTACCAGTGAAGTTACTCAGACTAA
TAAAGGAGCAACGAAAAACAAGTTTTCCACTGATCTTATTTGTATCAGAGATTGAATTAGGAGAAAAGCTCCTTAACCTC
TTAAGACAGAACTTCAAGGATGAAATCATCGAACTGGTGACCTCTAAAACAGAAAATAGGTTAGAACTGGTAGAAAAATT
TCGCAACCAAGAAATTACCATCCTTGTTTCAACGACAATCCTGGAAAGGGGAGTTACCTTCCCTAAAGTGGATGTGTTTG
TGATTGAGGCCAATCATCGGCTGTTCACTAAGAGCACCCTGGTTCAAATCGCTGGTCGTGTTGGAAGAAGTATGGAAAGA
CCCACAGGCGAGTTGCTTTTCCTAGCAGAAGGAACCAGCCAAGAAATGACACAAGCCATTAAAGAAATAAAAGAAATGAA
TCAGGAGGCAGGGTTTTGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-396)

Type III restriction enzyme, res subunit (ResIII)

(95-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

62.818

100

0.63
  comFA/cflA Streptococcus mitis SK321

62.587

100

0.627
  comFA/cflA Streptococcus pneumoniae D39

62.356

100

0.625
  comFA/cflA Streptococcus pneumoniae R6

62.356

100

0.625
  comFA/cflA Streptococcus pneumoniae TIGR4

62.356

100

0.625
  comFA/cflA Streptococcus pneumoniae Rx1

62.356

100

0.625
  comFA Lactococcus lactis subsp. cremoris KW2

52.538

91.204

0.479
  comFA Latilactobacillus sakei subsp. sakei 23K

38.889

100

0.389

Multiple sequence alignment