Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   N597_RS01615 Genome accession   NC_022582
Coordinates   325076..326374 (+) Length   432 a.a.
NCBI ID   WP_023022371.1    Uniprot ID   -
Organism   Streptococcus ilei     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 320076..331374
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N597_RS01590 (N597_01645) - 320591..321223 (+) 633 WP_023022361.1 response regulator transcription factor -
  N597_RS01595 (N597_01650) - 321268..322674 (+) 1407 WP_023022363.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  N597_RS01600 (N597_01655) - 322671..323039 (+) 369 WP_023022365.1 S1 RNA-binding domain-containing protein -
  N597_RS01605 (N597_01660) cysK 323367..324296 (-) 930 WP_023022367.1 cysteine synthase A -
  N597_RS01610 (N597_01665) - 324388..325020 (-) 633 WP_023022369.1 YigZ family protein -
  N597_RS01615 (N597_01670) comFA/cflA 325076..326374 (+) 1299 WP_023022371.1 DEAD/DEAH box helicase Machinery gene
  N597_RS01620 (N597_01675) - 326437..327042 (+) 606 WP_224781598.1 ComF family protein -
  N597_RS01625 (N597_01680) hpf 327130..327675 (+) 546 WP_023022375.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49775.20 Da        Isoelectric Point: 9.4826

>NTDB_id=62896 N597_RS01615 WP_023022371.1 325076..326374(+) (comFA/cflA) [Streptococcus ilei]
MKVEDCYGRLFTQEQLEVELLGQAQELPAMVEEKTGLFCNRCGTKIDKSKWKLQIGSYYCRACIQLGRVRSDQVLYYFLQ
QAFPQEEVLRWQGSLTPFQSRVSQELVQSLTDRKPMMVHAVTGAGKTEMMYQVVAETIKKGRCVCIATPRIDVCIELYKR
MTKDFSCPISLLHGDSEPYFRTPLVISTTHQLLKFYQAFDLLIIDEVDAFPFVDNPVLYHAVSNAVTKNGKLIYLTATST
KELDKKVKKQEINRVSLPRRFHGNPLVIPRKVWLKDLRKKVEKKQVPGKLLRLIKEQRKTSFPLILFVSEIELGEKLLNL
LRQNFKDEIIELVTSKTENRLELVEKFRNQEITILVSTTILERGVTFPKVDVFVIEANHRLFTKSTLVQIAGRVGRSMER
PTGELLFLAEGTSQEMTQAIKEIKEMNREAGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=62896 N597_RS01615 WP_023022371.1 325076..326374(+) (comFA/cflA) [Streptococcus ilei]
ATGAAAGTTGAAGATTGTTATGGAAGGTTGTTCACCCAAGAACAACTAGAGGTGGAACTGCTTGGACAAGCCCAAGAACT
GCCAGCTATGGTAGAGGAAAAGACGGGCTTGTTTTGTAATCGGTGTGGGACTAAGATTGATAAAAGCAAATGGAAACTAC
AGATAGGAAGCTACTATTGTAGAGCCTGCATTCAATTAGGAAGAGTTAGGAGCGACCAAGTACTCTATTACTTTCTCCAG
CAAGCCTTTCCACAGGAAGAAGTCCTAAGATGGCAGGGGAGCTTGACGCCATTTCAAAGTCGGGTTTCTCAAGAGTTGGT
TCAATCCTTAACAGATAGAAAGCCTATGATGGTACACGCAGTTACAGGAGCAGGTAAAACGGAAATGATGTACCAAGTGG
TAGCGGAAACGATTAAAAAAGGGAGATGTGTTTGCATTGCTACACCAAGGATTGACGTGTGTATTGAATTATATAAGCGA
ATGACAAAGGACTTTTCCTGCCCCATCTCGTTGTTGCACGGTGATTCAGAACCTTATTTCCGAACGCCTCTCGTCATATC
CACCACACATCAACTATTAAAATTTTATCAAGCTTTTGACCTCCTCATAATCGATGAAGTCGATGCCTTTCCTTTTGTTG
ATAACCCTGTTCTCTACCATGCCGTTTCAAATGCCGTAACCAAGAATGGAAAGCTCATCTATTTGACAGCTACCTCAACA
AAAGAGTTAGATAAAAAGGTCAAAAAACAGGAAATAAACCGCGTTAGCCTACCCAGACGCTTTCACGGAAACCCTCTAGT
AATTCCTAGAAAAGTATGGCTAAAAGATCTACGAAAGAAAGTAGAAAAGAAGCAAGTACCAGGGAAGTTACTCAGACTAA
TAAAGGAGCAACGAAAAACAAGCTTTCCACTGATCTTATTTGTATCAGAGATTGAATTAGGAGAAAAGCTCCTTAACCTC
TTAAGACAGAACTTCAAGGATGAAATCATCGAACTGGTGACCTCTAAAACAGAAAATAGGTTAGAACTGGTAGAAAAATT
TCGCAACCAAGAAATTACAATCCTTGTTTCAACGACAATCCTGGAAAGGGGAGTTACCTTCCCTAAAGTAGATGTGTTTG
TGATTGAGGCCAATCATCGGCTGTTCACTAAGAGCACCCTGGTTCAAATCGCTGGTCGTGTAGGAAGAAGTATGGAAAGA
CCCACAGGCGAATTACTTTTTCTAGCAGAAGGAACCAGCCAAGAAATGACACAAGCCATTAAAGAAATAAAAGAAATGAA
TCGGGAGGCAGGATTTTGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-396)

Type III restriction enzyme, res subunit (ResIII)

(95-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

62.587

100

0.627
  comFA/cflA Streptococcus mitis SK321

62.356

100

0.625
  comFA/cflA Streptococcus pneumoniae D39

62.125

100

0.623
  comFA/cflA Streptococcus pneumoniae R6

62.125

100

0.623
  comFA/cflA Streptococcus pneumoniae TIGR4

62.125

100

0.623
  comFA/cflA Streptococcus pneumoniae Rx1

62.125

100

0.623
  comFA Lactococcus lactis subsp. cremoris KW2

52.792

91.204

0.481
  comFA Latilactobacillus sakei subsp. sakei 23K

38.161

100

0.384

Multiple sequence alignment