Detailed information NTG0628880

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: N4267_RS04725
• Genome accession: NZ_CP104354
• Coordinates: 1005811..1007091 (+)
• Length: 426 a.a.
• NCBI ID: WP_000130332.1
• Uniprot ID: A0AAU8WEE3
• Organism: Vibrio cholerae strain PNUSAV001140
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1000811..1012091

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N4267_RS04705 (N4267_04705)	-	1001406..1003199 (-)	1794	WP_134987213.1	sensor histidine kinase	-
N4267_RS04710 (N4267_04710)	-	1003189..1003407 (+)	219	WP_001881672.1	hypothetical protein	-
N4267_RS04715 (N4267_04715)	tig	1003698..1004999 (+)	1302	WP_001198446.1	trigger factor	-
N4267_RS04720 (N4267_04720)	clpP	1005105..1005731 (+)	627	WP_000121678.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
N4267_RS04725 (N4267_04725)	clpX	1005811..1007091 (+)	1281	WP_000130332.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
N4267_RS04730 (N4267_04730)	lon	1007214..1009574 (+)	2361	WP_001047609.1	endopeptidase La	-
N4267_RS04735 (N4267_04735)	-	1009758..1010030 (+)	273	WP_001044516.1	HU family DNA-binding protein	-
N4267_RS04740 (N4267_04740)	ppiD	1010183..1012042 (+)	1860	WP_134987212.1	peptidylprolyl isomerase	-

Sequence

Protein

• Length: 426 a.a.
• Molecular weight: 46490.23 Da
• Isoelectric Point: 4.7780

>NTDB_id=628880 N4267_RS04725 WP_000130332.1 1005811..1007091(+) (clpX) [Vibrio cholerae strain PNUSAV001140]
MTDKSKEGGSSKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKKESAALPTPRKIREHLDDYVI
GQEHAKKVLAVAVYNHYKRLRNGDTTSEGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVAKAERGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTSKILFICGGAFAGLDKVIEQRVATGTGIGFGADVRSKDNSKTLSELFTQVEPEDLVKYGLIPEFIGRLPVTATLTELD
EAALIQILCEPKNALTKQYAALFELENVDLEFREDALKAIAAKAMKRKTGARGLRSILEAVLLETMYELPSMEEVSKVVI
DESVINGESAPLLIYSANESQAAGAE

Nucleotide

• Length: 1281 bp

>NTDB_id=628880 N4267_RS04725 WP_000130332.1 1005811..1007091(+) (clpX) [Vibrio cholerae strain PNUSAV001140]
ATGACAGATAAAAGCAAAGAGGGCGGTAGTAGTAAACTGCTGTACTGCTCTTTCTGTGGCAAAAGCCAGCACGAAGTTCG
CAAACTGATCGCAGGTCCGTCCGTGTATATTTGTGATGAGTGCGTTGATTTATGCAACGACATCATCCGCGAAGAGATCA
AAGATGTTCTGCCAAAAAAGGAATCAGCGGCGTTGCCGACGCCAAGAAAGATTCGTGAACATCTCGACGATTATGTGATT
GGTCAAGAACACGCCAAAAAAGTGCTAGCCGTTGCGGTATATAACCACTACAAGCGTTTACGTAATGGTGATACGACTAG
CGAAGGCGTTGAGCTGGGCAAGAGTAACATTTTGCTGATTGGCCCAACGGGTAGCGGTAAAACACTACTGGCTGAAACGC
TGGCGCGTTTGCTGGATGTGCCATTTACCATGGCGGATGCGACCACATTAACCGAGGCGGGTTATGTGGGCGAAGATGTA
GAAAATATCATTCAAAAGCTGCTGCAAAAATGCGATTACGATGTTGCAAAAGCGGAGCGTGGTATCGTCTATATCGATGA
AATTGACAAAATTTCTCGTAAGTCTGAAAACCCATCCATCACACGTGACGTGTCGGGTGAAGGGGTTCAGCAAGCGCTGT
TAAAACTGATTGAAGGTACAGTTGCTTCGGTTCCACCACAAGGTGGCCGTAAACATCCTCAGCAGGAATTCCTGCAAGTC
GACACCTCAAAAATCCTATTTATCTGTGGTGGCGCGTTTGCTGGCCTAGATAAAGTGATTGAACAGCGTGTTGCGACAGG
GACTGGTATCGGTTTTGGCGCGGATGTGCGTTCTAAAGACAACAGCAAAACCTTGAGCGAACTGTTTACTCAGGTTGAAC
CTGAAGATTTGGTGAAATACGGTTTGATCCCAGAGTTCATTGGTCGTCTGCCTGTTACGGCAACGCTGACTGAACTGGAT
GAAGCGGCATTGATTCAAATTCTGTGTGAACCAAAGAATGCACTGACCAAACAGTATGCGGCGTTGTTTGAACTGGAAAA
CGTTGATCTGGAGTTTCGTGAAGATGCGCTGAAAGCGATTGCCGCTAAAGCGATGAAGCGTAAAACCGGTGCACGTGGTC
TACGTTCAATCCTTGAAGCAGTTCTACTGGAAACCATGTATGAACTGCCTTCAATGGAAGAGGTCAGCAAGGTGGTGATT
GATGAATCTGTGATCAACGGAGAGTCCGCACCGCTACTGATTTACAGCGCTAATGAGAGCCAAGCCGCTGGTGCGGAGTA
A

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (14-51)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (319-396)

• AAA domain (Cdc48 subfamily) (AAA_2) (114-312)

3D structure

• AlphaFold DB: A0AAU8WEE3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	58.706	94.366	0.554
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	53.333	95.07	0.507