Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   N2A94_RS06510 Genome accession   NZ_CP104048
Coordinates   1280920..1281561 (-) Length   213 a.a.
NCBI ID   WP_003107492.1    Uniprot ID   A0ABP2SXX6
Organism   Streptococcus parauberis strain KSP20     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1275920..1286561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N2A94_RS06485 (N2A94_06485) comFA/cflA 1276012..1277316 (-) 1305 WP_045407612.1 DEAD/DEAH box helicase Machinery gene
  N2A94_RS06490 (N2A94_06490) - 1277373..1278005 (+) 633 WP_003107489.1 YigZ family protein -
  N2A94_RS06495 (N2A94_06495) cysK 1278128..1279057 (+) 930 WP_003103108.1 cysteine synthase A -
  N2A94_RS06500 (N2A94_06500) - 1279133..1279486 (-) 354 WP_003103672.1 S1 RNA-binding domain-containing protein -
  N2A94_RS06505 (N2A94_06505) - 1279486..1280886 (-) 1401 WP_045407608.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  N2A94_RS06510 (N2A94_06510) vraR 1280920..1281561 (-) 642 WP_003107492.1 response regulator transcription factor Regulator
  N2A94_RS06515 (N2A94_06515) - 1281554..1282558 (-) 1005 WP_003107494.1 sensor histidine kinase -
  N2A94_RS06520 (N2A94_06520) liaF 1282555..1283250 (-) 696 WP_037620823.1 cell wall-active antibiotics response protein LiaF -
  N2A94_RS06525 (N2A94_06525) pknB 1283401..1285140 (-) 1740 WP_003107495.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  N2A94_RS06530 (N2A94_06530) - 1285140..1285880 (-) 741 WP_003102848.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23957.60 Da        Isoelectric Point: 4.7106

>NTDB_id=626739 N2A94_RS06510 WP_003107492.1 1280920..1281561(-) (vraR) [Streptococcus parauberis strain KSP20]
MDKIRVILVDDHEMVRLGLKSFLNMQKDIEVIGEASNGRQGIDLALELRPDVLVMDLVMPEMGGVEATLDILSKWTEAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRKVAKGQLAIETEVDKKIKEHDKNPELHEELTAREFDILYLLA
KGYDNQTIADELFISLKTVKTHVSNILSKLDVDDRTQAVVYAFQHHIVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=626739 N2A94_RS06510 WP_003107492.1 1280920..1281561(-) (vraR) [Streptococcus parauberis strain KSP20]
ATGGATAAAATACGTGTCATATTAGTTGATGACCATGAGATGGTGCGTTTAGGCTTAAAAAGCTTCTTAAATATGCAAAA
AGACATAGAAGTTATTGGTGAAGCATCTAATGGTCGCCAAGGCATTGATTTAGCTTTAGAACTACGTCCAGATGTTTTAG
TCATGGATTTAGTGATGCCTGAAATGGGTGGAGTTGAAGCAACATTAGATATTCTTTCAAAATGGACAGAAGCTAAAGTT
TTAGTACTGACTTCCTATCTTGATAATGAGAAAATCTATCCAGTTATTGATGCCGGAGCCAAAGGTTATATGTTAAAGAC
TTCAAGTGCTGCAGAAATCTTAAATGCAATTAGAAAAGTAGCAAAAGGCCAACTAGCTATCGAGACAGAAGTTGACAAAA
AAATAAAAGAGCATGATAAAAATCCAGAATTGCATGAGGAGTTAACAGCTCGGGAATTTGATATTTTATATCTGTTAGCC
AAAGGTTATGATAATCAAACGATTGCTGATGAGTTATTTATTTCATTAAAAACTGTAAAAACACATGTTTCAAATATTCT
TTCTAAATTGGACGTCGACGATCGAACACAAGCTGTAGTCTACGCATTCCAACACCATATAGTGCCACAAGATGACAATT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.913

96.714

0.512
  degU Bacillus subtilis subsp. subtilis str. 168

35.586

100

0.371