Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NZD79_RS03640 Genome accession   NZ_CP103972
Coordinates   712328..712984 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain DLI.5a     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 707328..717984
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NZD79_RS03595 (NZD79_03595) - 707415..707495 (+) 81 Protein_720 hypothetical protein -
  NZD79_RS03600 (NZD79_03600) - 707492..708643 (+) 1152 WP_032230609.1 IS30-like element IS30 family transposase -
  NZD79_RS03605 (NZD79_03605) - 708656..708958 (-) 303 Protein_722 transposase -
  NZD79_RS03610 (NZD79_03610) - 708993..709196 (+) 204 Protein_723 hypothetical protein -
  NZD79_RS03630 (NZD79_03630) pgsA 709894..710442 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NZD79_RS03635 (NZD79_03635) uvrC 710499..712331 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NZD79_RS03640 (NZD79_03640) letA 712328..712984 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NZD79_RS24610 - 713126..713197 (+) 72 Protein_727 transcriptional regulator -
  NZD79_RS03645 (NZD79_03645) yecU 713280..713456 (+) 177 WP_000590347.1 protein YecU -
  NZD79_RS03650 (NZD79_03650) yecF 713443..713667 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  NZD79_RS03655 (NZD79_03655) sdiA 713735..714457 (-) 723 WP_001152713.1 transcriptional regulator SdiA -
  NZD79_RS03660 (NZD79_03660) tcyN 714687..715439 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NZD79_RS03665 (NZD79_03665) tcyL 715436..716104 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  NZD79_RS03670 (NZD79_03670) dcyD 716119..717105 (-) 987 WP_097342233.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=626019 NZD79_RS03640 WP_000611328.1 712328..712984(-) (letA) [Escherichia coli strain DLI.5a]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=626019 NZD79_RS03640 WP_000611328.1 712328..712984(-) (letA) [Escherichia coli strain DLI.5a]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCAACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGTCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482