Detailed information    

insolico Bioinformatically predicted

Overview

Name   eeP   Type   Regulator
Locus tag   LNB41_RS10725 Genome accession   NZ_CP086592
Coordinates   2184155..2185423 (-) Length   422 a.a.
NCBI ID   WP_002362168.1    Uniprot ID   -
Organism   Enterococcus faecalis strain Fac74     
Function   processing of ComS (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2186341..2254166 2184155..2185423 flank 918


Gene organization within MGE regions


Location: 2184155..2254166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LNB41_RS10725 (LNB41_10725) eeP 2184155..2185423 (-) 1269 WP_002362168.1 RIP metalloprotease RseP Regulator
  LNB41_RS10730 (LNB41_10730) - 2185839..2186618 (+) 780 WP_229023926.1 SDR family oxidoreductase -
  LNB41_RS10735 (LNB41_10735) - 2186703..2187305 (+) 603 WP_104670785.1 YczE/YyaS/YitT family protein -
  LNB41_RS10740 (LNB41_10740) - 2187723..2189390 (-) 1668 WP_010820171.1 RNA-directed DNA polymerase -
  LNB41_RS10745 (LNB41_10745) - 2189454..2189720 (-) 267 WP_010820172.1 hypothetical protein -
  LNB41_RS10750 (LNB41_10750) - 2189843..2191600 (-) 1758 WP_010820173.1 DEAD/DEAH box helicase -
  LNB41_RS10755 (LNB41_10755) - 2191607..2192560 (-) 954 WP_010820174.1 DUF1837 domain-containing protein -
  LNB41_RS10760 (LNB41_10760) - 2193772..2194380 (-) 609 Protein_2105 replication protein -
  LNB41_RS10765 (LNB41_10765) - 2194484..2194915 (-) 432 WP_229022067.1 hypothetical protein -
  LNB41_RS10770 (LNB41_10770) - 2194908..2196476 (-) 1569 Protein_2107 restriction endonuclease -
  LNB41_RS10775 (LNB41_10775) - 2196870..2198120 (+) 1251 WP_001573639.1 IS110 family transposase -
  LNB41_RS10780 (LNB41_10780) - 2198353..2199336 (-) 984 WP_025479786.1 protein rep -
  LNB41_RS10785 (LNB41_10785) mobV 2199613..2200875 (-) 1263 WP_000119405.1 MobV family relaxase -
  LNB41_RS10790 (LNB41_10790) catA 2201165..2201812 (-) 648 WP_002415230.1 type A chloramphenicol O-acetyltransferase -
  LNB41_RS10795 (LNB41_10795) - 2201947..2202258 (-) 312 Protein_2112 replication initiation protein -
  LNB41_RS10800 (LNB41_10800) tet(L) 2202854..2204230 (-) 1377 WP_104670783.1 tetracycline efflux MFS transporter Tet(L) -
  LNB41_RS15390 - 2204264..2204326 (-) 63 Protein_2114 tetracycline resistance efflux system leader peptide -
  LNB41_RS10805 (LNB41_10805) tet(M) 2204429..2206348 (-) 1920 WP_104670782.1 tetracycline resistance ribosomal protection protein Tet(M) -
  LNB41_RS15395 - 2206364..2206411 (-) 48 Protein_2116 hypothetical protein -
  LNB41_RS10815 (LNB41_10815) - 2206725..2207657 (-) 933 WP_104670802.1 conjugal transfer protein -
  LNB41_RS10820 (LNB41_10820) - 2207654..2208655 (-) 1002 WP_104670801.1 lysozyme family protein -
  LNB41_RS10825 (LNB41_10825) - 2208652..2210829 (-) 2178 WP_061406561.1 CD3337/EF1877 family mobilome membrane protein -
  LNB41_RS10830 (LNB41_10830) - 2210832..2213279 (-) 2448 WP_000331160.1 ATP-binding protein -
  LNB41_RS10835 (LNB41_10835) - 2213263..2213655 (-) 393 WP_267483698.1 conjugal transfer protein -
  LNB41_RS10840 (LNB41_10840) - 2213744..2214241 (-) 498 WP_000342539.1 antirestriction protein ArdA -
  LNB41_RS10845 (LNB41_10845) - 2214358..2214579 (-) 222 WP_001009056.1 hypothetical protein -
  LNB41_RS10850 (LNB41_10850) mobT 2214622..2215827 (-) 1206 WP_000398284.1 MobT family relaxase -
  LNB41_RS10855 (LNB41_10855) - 2215850..2216002 (-) 153 WP_000879507.1 hypothetical protein -
  LNB41_RS10860 (LNB41_10860) - 2216005..2217390 (-) 1386 Protein_2126 FtsK/SpoIIIE domain-containing protein -
  LNB41_RS10865 (LNB41_10865) - 2217419..2217805 (-) 387 WP_176438289.1 YdcP family protein -
  LNB41_RS10870 (LNB41_10870) - 2217821..2218135 (-) 315 WP_000420682.1 YdcP family protein -
  LNB41_RS10875 (LNB41_10875) - 2218511..2218675 (-) 165 WP_159162055.1 hypothetical protein -
  LNB41_RS10880 (LNB41_10880) - 2218805..2219581 (-) 777 WP_104670800.1 hypothetical protein -
  LNB41_RS10885 (LNB41_10885) - 2219640..2219876 (-) 237 WP_104670799.1 helix-turn-helix domain-containing protein -
  LNB41_RS10890 (LNB41_10890) - 2219990..2220658 (+) 669 WP_229022069.1 hypothetical protein -
  LNB41_RS10895 (LNB41_10895) - 2220844..2221098 (-) 255 WP_104670798.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
  LNB41_RS10900 (LNB41_10900) - 2221144..2221542 (-) 399 WP_104670797.1 hypothetical protein -
  LNB41_RS10905 (LNB41_10905) - 2222048..2222233 (-) 186 WP_050047021.1 hypothetical protein -
  LNB41_RS10910 (LNB41_10910) - 2222237..2224600 (-) 2364 WP_181033968.1 pLS20_p028 family conjugation system transmembrane protein -
  LNB41_RS10915 (LNB41_10915) - 2224603..2224815 (-) 213 WP_104670796.1 hypothetical protein -
  LNB41_RS10920 (LNB41_10920) - 2224815..2225681 (-) 867 WP_104670795.1 hypothetical protein -
  LNB41_RS10925 (LNB41_10925) - 2225898..2226197 (-) 300 WP_104670794.1 helix-turn-helix domain-containing protein -
  LNB41_RS10930 (LNB41_10930) - 2226359..2227141 (+) 783 WP_104670793.1 helix-turn-helix domain-containing protein -
  LNB41_RS10935 (LNB41_10935) - 2227194..2228336 (+) 1143 WP_104670792.1 site-specific integrase -
  LNB41_RS10940 (LNB41_10940) sufB 2228435..2229829 (-) 1395 WP_002356769.1 Fe-S cluster assembly protein SufB -
  LNB41_RS10945 (LNB41_10945) sufU 2229848..2230315 (-) 468 WP_002356768.1 Fe-S cluster assembly sulfur transfer protein SufU -
  LNB41_RS10950 (LNB41_10950) - 2230302..2231537 (-) 1236 WP_002407165.1 cysteine desulfurase -
  LNB41_RS10955 (LNB41_10955) sufD 2231534..2232820 (-) 1287 WP_010816021.1 Fe-S cluster assembly protein SufD -
  LNB41_RS10960 (LNB41_10960) sufC 2232835..2233605 (-) 771 WP_002356763.1 Fe-S cluster assembly ATPase SufC -
  LNB41_RS10965 (LNB41_10965) frr 2233975..2234532 (-) 558 WP_002356762.1 ribosome recycling factor -
  LNB41_RS10970 (LNB41_10970) pyrH 2234536..2235258 (-) 723 WP_002356761.1 UMP kinase -
  LNB41_RS10975 (LNB41_10975) tsf 2235519..2236400 (-) 882 WP_002356760.1 translation elongation factor Ts -
  LNB41_RS10980 (LNB41_10980) rpsB 2236506..2237291 (-) 786 WP_002356759.1 30S ribosomal protein S2 -
  LNB41_RS10985 (LNB41_10985) - 2237475..2237912 (-) 438 WP_002368982.1 GNAT family N-acetyltransferase -
  LNB41_RS10990 (LNB41_10990) - 2237932..2238708 (-) 777 WP_010820175.1 TrmH family RNA methyltransferase -
  LNB41_RS10995 (LNB41_10995) - 2238815..2239090 (+) 276 WP_002356756.1 acylphosphatase -
  LNB41_RS11000 (LNB41_11000) yidC 2239257..2240189 (+) 933 WP_002356755.1 membrane protein insertase YidC -
  LNB41_RS11005 (LNB41_11005) - 2240223..2240414 (-) 192 WP_002382766.1 DNA-directed RNA polymerase subunit alpha C-terminal domain-containing protein -
  LNB41_RS11010 (LNB41_11010) glyS 2240454..2242538 (-) 2085 WP_010820176.1 glycine--tRNA ligase subunit beta -
  LNB41_RS11015 (LNB41_11015) glyQ 2242540..2243448 (-) 909 WP_002379669.1 glycine--tRNA ligase subunit alpha -
  LNB41_RS11020 (LNB41_11020) recO 2244184..2244972 (-) 789 WP_002356748.1 DNA repair protein RecO -
  LNB41_RS11025 (LNB41_11025) era 2245055..2245957 (-) 903 WP_002359745.1 GTPase Era -
  LNB41_RS11030 (LNB41_11030) - 2245971..2246372 (-) 402 WP_002382764.1 diacylglycerol kinase family protein -
  LNB41_RS11035 (LNB41_11035) ybeY 2246356..2246835 (-) 480 WP_002356745.1 rRNA maturation RNase YbeY -
  LNB41_RS11040 (LNB41_11040) - 2246835..2249033 (-) 2199 WP_002382763.1 HD family phosphohydrolase -
  LNB41_RS11045 (LNB41_11045) - 2249062..2249976 (-) 915 WP_369810298.1 PhoH family protein -
  LNB41_RS11050 (LNB41_11050) - 2250219..2250668 (-) 450 WP_002356741.1 GatB/YqeY domain-containing protein -
  LNB41_RS11055 (LNB41_11055) rpsU 2250694..2250870 (-) 177 WP_002356740.1 30S ribosomal protein S21 -
  LNB41_RS11060 (LNB41_11060) - 2251036..2251476 (-) 441 WP_002394710.1 Fur family transcriptional regulator -
  LNB41_RS11065 (LNB41_11065) - 2251575..2252432 (+) 858 WP_002382760.1 pyruvate, water dikinase regulatory protein -
  LNB41_RS11070 (LNB41_11070) thrB 2252474..2253337 (-) 864 WP_002384228.1 homoserine kinase -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 46486.46 Da        Isoelectric Point: 6.6651

>NTDB_id=625631 LNB41_RS10725 WP_002362168.1 2184155..2185423(-) (eeP) [Enterococcus faecalis strain Fac74]
MKTIITFIIVFGILVLVHEFGHFYFAKRAGILVREFAIGMGPKIFAHRGKDGTTYTIRLLPIGGYVRMAGMGEDMTEITP
GMPLSVELNAVGNVVKINTSKKVQLPHSIPMEVVDFDLEKELFIKGYVNGNEEEETVYKVDHDATIIESDGTEVRIAPLD
VQFQSAKLSQRILTNFAGPMNNFILGFILFTLAVFLQGGVTDLNTNQIGQVIPNGPAAEAGLKENDKVLSINNQKIKKYE
DFTTIVQKNPEKPLTFVVERNGKEEQLTVTPEKQKVEKQTIGKVGVYPYMKTDLPSKLMGGIQDTLNSTTQIFKALGSLF
TGFSLNKLGGPVMMFKLSEEASNAGVSTVVFLMAMLSMNLGIINLLPIPALDGGKIVLNIIEGVRGKPISPEKEGIITLI
GFGFVMVLMVLVTWNDIQRFFF

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=625631 LNB41_RS10725 WP_002362168.1 2184155..2185423(-) (eeP) [Enterococcus faecalis strain Fac74]
ATGAAAACAATTATAACATTCATTATTGTCTTCGGTATTCTTGTCCTCGTACATGAATTTGGCCACTTTTATTTTGCAAA
ACGAGCGGGTATTTTAGTTCGTGAGTTTGCAATCGGAATGGGACCAAAGATTTTTGCGCATCGTGGAAAAGATGGCACCA
CTTATACGATTCGCTTATTGCCAATTGGTGGCTATGTGCGAATGGCTGGGATGGGCGAAGACATGACAGAAATCACACCA
GGTATGCCTCTATCTGTTGAGTTAAATGCCGTGGGTAATGTGGTTAAAATTAATACAAGTAAAAAAGTACAATTACCTCA
TAGTATTCCGATGGAAGTCGTTGATTTTGATCTTGAAAAAGAATTATTCATCAAGGGCTATGTCAATGGAAACGAGGAAG
AAGAAACCGTTTATAAAGTTGACCATGATGCAACGATTATTGAAAGTGATGGAACCGAGGTGCGGATTGCGCCACTTGAC
GTTCAATTTCAATCAGCGAAATTATCGCAACGCATTTTGACGAACTTTGCGGGACCCATGAATAACTTTATCTTAGGGTT
TATTCTGTTTACGTTAGCGGTCTTTCTACAAGGAGGCGTCACTGATTTAAACACGAACCAAATTGGACAAGTGATTCCTA
ATGGCCCAGCCGCAGAAGCTGGGTTGAAAGAAAACGATAAAGTCTTATCGATTAATAATCAAAAAATCAAAAAATACGAA
GATTTTACAACCATTGTGCAGAAGAACCCCGAAAAGCCGTTAACGTTCGTAGTTGAGCGTAACGGCAAAGAAGAGCAACT
AACAGTGACACCAGAAAAACAAAAAGTGGAAAAACAAACAATTGGTAAAGTCGGCGTTTATCCTTATATGAAAACCGATT
TACCGTCAAAATTGATGGGCGGTATTCAGGATACTTTGAATAGTACGACACAGATTTTTAAAGCACTTGGCTCACTATTC
ACCGGTTTTAGCTTAAACAAACTAGGTGGGCCAGTCATGATGTTTAAATTATCGGAAGAAGCATCCAATGCTGGAGTAAG
TACAGTTGTATTCTTAATGGCCATGTTGTCAATGAACTTAGGGATTATTAATTTGTTGCCGATCCCAGCTTTAGATGGCG
GGAAAATTGTCTTAAACATTATTGAAGGTGTACGTGGAAAACCAATTAGTCCTGAAAAAGAAGGCATCATTACGTTAATT
GGCTTTGGGTTTGTCATGGTGTTAATGGTGTTAGTTACTTGGAACGATATTCAACGCTTTTTCTTTTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_6)

(208-260)

Peptidase family M50 (Peptidase_M50)

(6-408)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  eeP Streptococcus thermophilus LMD-9

53.738

100

0.545
  eeP Streptococcus thermophilus LMG 18311

53.738

100

0.545