Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   FNL60_RS08080 Genome accession   NZ_AP019720
Coordinates   1595842..1596483 (-) Length   213 a.a.
NCBI ID   WP_002263036.1    Uniprot ID   -
Organism   Streptococcus mutans strain NBRC 13955     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1590842..1601483
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNL60_RS08060 (SM3g_14990) - 1592280..1593026 (-) 747 WP_002263032.1 DeoR/GlpR family DNA-binding transcription regulator -
  FNL60_RS08065 (SM3g_15000) - 1593158..1593934 (+) 777 WP_002263033.1 glycyl-radical enzyme activating protein -
  FNL60_RS08070 (SM3g_15010) - 1594013..1594399 (-) 387 WP_002263034.1 S1 RNA-binding domain-containing protein -
  FNL60_RS08075 (SM3g_15020) - 1594383..1595798 (-) 1416 WP_002263035.1 Cof-type HAD-IIB family hydrolase -
  FNL60_RS08080 (SM3g_15030) vraR 1595842..1596483 (-) 642 WP_002263036.1 response regulator transcription factor Regulator
  FNL60_RS08085 (SM3g_15040) - 1596476..1597480 (-) 1005 WP_002272573.1 sensor histidine kinase -
  FNL60_RS08090 (SM3g_15050) liaF 1597477..1598172 (-) 696 WP_002263038.1 cell wall-active antibiotics response protein LiaF -
  FNL60_RS08095 (SM3g_15060) pknB 1598613..1600463 (-) 1851 WP_002263039.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FNL60_RS08100 (SM3g_15070) - 1600460..1601203 (-) 744 WP_002279923.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23824.40 Da        Isoelectric Point: 4.8864

>NTDB_id=62518 FNL60_RS08080 WP_002263036.1 1595842..1596483(-) (vraR) [Streptococcus mutans strain NBRC 13955]
MSKTKVILVDDHEMVRLGLKSFLNLQDNVEVIGEASNGRQGIDLALKLKPDVVVMDLVMPEMDGVEATLELLKDWKEAKI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVAKGDLAIETEVDKKIKDHHNNPDLHEDLTARERDILALLA
KGYDNQTIADELFISLKTVKTHVSNILSKLQVDDRTQAVVYAFQHHLVPQDEN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=62518 FNL60_RS08080 WP_002263036.1 1595842..1596483(-) (vraR) [Streptococcus mutans strain NBRC 13955]
ATGAGTAAAACAAAAGTTATACTGGTTGATGATCATGAAATGGTTCGATTGGGTTTGAAAAGTTTTCTTAATTTACAAGA
TAATGTAGAAGTTATCGGTGAGGCTAGCAATGGCCGTCAAGGTATTGACTTGGCTTTAAAATTAAAACCAGACGTTGTTG
TCATGGACTTGGTTATGCCAGAAATGGATGGTGTAGAAGCCACTCTTGAACTTCTAAAAGATTGGAAAGAAGCCAAAATT
CTAGTTTTAACCAGTTATTTAGATAACGAAAAAATTTATCCTGTCATTGAAGCAGGTGCTAAAGGTTATATGTTGAAAAC
TTCCAGTGCAGCTGAAATTTTGAATGCCATTCAAAAAGTAGCTAAGGGAGATTTAGCGATTGAAACAGAAGTTGATAAGA
AAATCAAGGATCATCATAATAATCCTGATTTGCATGAAGATTTAACAGCGCGTGAACGAGACATTTTGGCTTTACTTGCT
AAGGGTTATGATAACCAAACGATTGCTGATGAGCTTTTCATTTCTTTGAAGACTGTCAAAACACATGTTTCTAATATCTT
ATCGAAATTACAAGTTGATGATCGGACCCAAGCCGTTGTCTATGCTTTTCAGCATCATTTAGTGCCACAGGACGAAAATT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.22

96.244

0.493
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376