Detailed information NTG0624741

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: LMK00_RS02165
• Genome accession: NZ_CP086395
• Coordinates: 446795..448285 (+)
• Length: 496 a.a.
• NCBI ID: WP_252175613.1
• Uniprot ID: A0A9Q8Y2N7
• Organism: Lactococcus formosensis strain I4/6O
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 441795..453285

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LMK00_RS02140 (LMK00_02140)	pfkB	441933..442850 (+)	918	WP_252175612.1	1-phosphofructokinase	-
LMK00_RS02145 (LMK00_02145)	-	442884..444788 (+)	1905	WP_096368615.1	fructose-specific PTS transporter subunit EIIC	-
LMK00_RS02150 (LMK00_02150)	-	444900..445142 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
LMK00_RS02155 (LMK00_02155)	-	445360..445911 (+)	552	WP_165713171.1	YceD family protein	-
LMK00_RS02160 (LMK00_02160)	covR	446012..446707 (+)	696	WP_017368870.1	response regulator transcription factor	Regulator
LMK00_RS02165 (LMK00_02165)	covS	446795..448285 (+)	1491	WP_252175613.1	HAMP domain-containing histidine kinase	Regulator
LMK00_RS02170 (LMK00_02170)	-	448681..450252 (+)	1572	WP_165713172.1	ABC transporter permease subunit	-
LMK00_RS02175 (LMK00_02175)	-	450253..450990 (+)	738	WP_165714351.1	amino acid ABC transporter ATP-binding protein	-
LMK00_RS02180 (LMK00_02180)	murD	451129..452490 (+)	1362	WP_252175614.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56885.94 Da
• Isoelectric Point: 5.2104

>NTDB_id=624741 LMK00_RS02165 WP_252175613.1 446795..448285(+) (covS) [Lactococcus formosensis strain I4/6O]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMRALNNVEQSLSQSVNKLS
EENLANYLAYAKGYTASSQGRENELETLGSMIGSRKSFYVFDVGENLIYSTNSYGFPLRKDVGDSSQAVRTFGEYSGYLV
ERPVHSKKTGELIGYVQAFYDMSYYYSVRTKLLVALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEKLATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLESIDFQDEDLICDPTEVSNFLKKNFLLIHPDLKLTVENDLPSGRLAHIYPNHYEQGLKILIDNAI
KYSPEDRQEVKIHLEEDDEYIITTVEDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYEGDVSVTS
VVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=624741 LMK00_RS02165 WP_252175613.1 446795..448285(+) (covS) [Lactococcus formosensis strain I4/6O]
ATGGTAAAATTTTTTGATTCTAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGGAGCATCATGCTACGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACTTTCACTATTTTTACAGTATTGGTTTATCAACTAACGATAACTACTTTCA
TCAATTCTGAAAAAGAGGATATGATGAGGGCTTTAAATAATGTTGAACAAAGTCTGTCCCAATCGGTAAACAAACTGTCA
GAAGAAAATCTTGCGAATTATTTGGCTTATGCCAAAGGCTATACAGCCTCCAGTCAGGGAAGAGAAAATGAACTTGAAAC
ACTAGGAAGTATGATTGGTTCAAGAAAGTCCTTTTATGTCTTCGATGTAGGTGAGAACCTGATTTACTCCACCAATTCGT
ATGGTTTTCCTCTAAGGAAAGATGTGGGTGATTCATCGCAAGCTGTACGTACATTTGGCGAATATTCTGGTTATTTGGTT
GAGCGACCTGTGCATTCTAAAAAAACGGGTGAACTGATCGGCTATGTACAGGCTTTTTATGATATGAGCTATTATTATAG
TGTGCGTACAAAGCTACTTGTTGCCTTGATTATCTTAGAAATTATAGCTCTCTTTATAGCTCAGTTTGTTGGTTACTTTA
TGGCGAGTCGCTATATCAAGCCTTTGGAACGTTTGCACGATGCAATCACTACACGTGCCAATAATTTGAAAGCAGATTTC
AAACCTGTCGTTATTCAGACAGGGGATGAAATTGAGAAACTTGCAACAGTTTATAATGATATGATGATCAAGCTTAATGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCCGATGTCAGTCATGAGTTACGGACGCCACTTGCAGTTTTGGATGGGCATT
TGAATCTCTTGAATCGTTGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTTAGT
ACGATGAGAACGATGTTGGAAGAGATGCTCGCATTGGCGCGTCTTGAAAGCATTGATTTTCAAGATGAAGACCTAATCTG
TGATCCGACAGAAGTTTCGAATTTTCTTAAGAAAAATTTTCTACTCATCCATCCTGATTTAAAGTTAACTGTTGAAAATG
ACTTGCCATCAGGAAGATTAGCACATATATATCCCAACCATTATGAGCAAGGTTTGAAAATATTGATTGATAATGCGATA
AAATACTCGCCTGAAGATCGTCAAGAAGTCAAGATACATCTTGAAGAAGATGATGAATATATCATTACAACTGTGGAGGA
CCGTGGTTATGGTATTAGCCAAGAAGATTTAAAACATGTATTTGAACGTTTCTTCCGTGCGGATAAAGCACGAAATCGAG
ATATAGGAGGAACTGGGCTTGGGCTATCTATTATTCAACGTATAGTGGAGAACTATGAGGGAGATGTTAGCGTGACTTCC
GTTGTAGGAGAGGGTTCAAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• HAMP domain (HAMP) (214-266)

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• ArlS sensor domain (ArlS_N) (52-190)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.332	100	0.554