Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   LMK00_RS02160 Genome accession   NZ_CP086395
Coordinates   446012..446707 (+) Length   231 a.a.
NCBI ID   WP_017368870.1    Uniprot ID   A0A9Q8Y2F9
Organism   Lactococcus formosensis strain I4/6O     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 441012..451707
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LMK00_RS02135 (LMK00_02135) - 441235..441936 (+) 702 WP_017368868.1 DeoR/GlpR family DNA-binding transcription regulator -
  LMK00_RS02140 (LMK00_02140) pfkB 441933..442850 (+) 918 WP_252175612.1 1-phosphofructokinase -
  LMK00_RS02145 (LMK00_02145) - 442884..444788 (+) 1905 WP_096368615.1 fructose-specific PTS transporter subunit EIIC -
  LMK00_RS02150 (LMK00_02150) - 444900..445142 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  LMK00_RS02155 (LMK00_02155) - 445360..445911 (+) 552 WP_165713171.1 YceD family protein -
  LMK00_RS02160 (LMK00_02160) covR 446012..446707 (+) 696 WP_017368870.1 response regulator transcription factor Regulator
  LMK00_RS02165 (LMK00_02165) covS 446795..448285 (+) 1491 WP_252175613.1 HAMP domain-containing histidine kinase Regulator
  LMK00_RS02170 (LMK00_02170) - 448681..450252 (+) 1572 WP_165713172.1 ABC transporter permease subunit -
  LMK00_RS02175 (LMK00_02175) - 450253..450990 (+) 738 WP_165714351.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 27023.75 Da        Isoelectric Point: 5.2713

>NTDB_id=624740 LMK00_RS02160 WP_017368870.1 446012..446707(+) (covR) [Lactococcus formosensis strain I4/6O]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQDNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTVEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=624740 LMK00_RS02160 WP_017368870.1 446012..446707(+) (covR) [Lactococcus formosensis strain I4/6O]
ATGAATTCATCTAAACGTATTTTAATTATCGAGGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGGTATCAAACTGCGGTTCAAGACAATGGTCGTAAAGGTCTTGAAGAAGCGATGTCAAAAGATTATGATTTGATTTTGC
TTGACTTAATGCTCCCAGAGCTGGATGGCTTTGAAGTTGCACGACGCTTACGCCGTGAAAAAGATACACATATTATCATG
ATGACTGCACGTGATTCAACAATGGACCGTGTTGCTGGTCTTGATATTGGAGCGGATGATTATATTACAAAACCATTCGC
AATTGAAGAGTTGTTAGCACGTGTGCGTTCACTCTTCCGTCGTGAAGATCATATCCATACTGTTGAAAAGTCAGACAACA
CTTCATTCCGTGACTTGGTAATTGATAAAACAAACCGCACAGTACACCGTGGTAAAAAAGTCATTGACCTTACACGTCGT
GAGTACGACTTACTCTTGACTTTGATGCAAAATGTGGGGGATGTCGTAACACGCGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTTGACGTTTATATCCGTTACCTACGTAACAAGATTGATGTCGAAGGCCGTG
AAAGTTATATCCAAACTGTTCGTGGCATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-116)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

88.646

99.134

0.879
  covR Streptococcus salivarius strain HSISS4

66.81

100

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424