Detailed information NTG0624726

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: M5R22_RS17525
• Genome accession: NZ_CP103742
• Coordinates: 3569677..3570951 (-)
• Length: 424 a.a.
• NCBI ID: WP_000130299.1
• Uniprot ID: -
• Organism: Escherichia coli O25b:H4-ST131 strain 2822
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3564677..3575951

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M5R22_RS17515 (M5R22_17515)	hupB	3566654..3566926 (-)	273	WP_001043542.1	nucleoid-associated protein HU-beta	-
M5R22_RS17520 (M5R22_17520)	lon	3567135..3569489 (-)	2355	WP_001295325.1	endopeptidase La	-
M5R22_RS17525 (M5R22_17525)	clpX	3569677..3570951 (-)	1275	WP_000130299.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
M5R22_RS17530 (M5R22_17530)	clpP	3571077..3571700 (-)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
M5R22_RS17535 (M5R22_17535)	tig	3571946..3573244 (-)	1299	WP_001198388.1	trigger factor	-
M5R22_RS17540 (M5R22_17540)	bolA	3573588..3573905 (-)	318	WP_000973448.1	transcriptional regulator BolA	-
M5R22_RS17545 (M5R22_17545)	yajG	3574210..3574788 (+)	579	WP_001295326.1	lipoprotein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46316.97 Da
• Isoelectric Point: 4.9297

>NTDB_id=624726 M5R22_RS17525 WP_000130299.1 3569677..3570951(-) (clpX) [Escherichia coli O25b:H4-ST131 strain 2822]
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIDGQSKPLLIYGKPEAQQASGE

Nucleotide

• Length: 1275 bp

>NTDB_id=624726 M5R22_RS17525 WP_000130299.1 3569677..3570951(-) (clpX) [Escherichia coli O25b:H4-ST131 strain 2822]
ATGACAGATAAACGCAAAGATGGCTCAGGCAAATTGCTGTATTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGCAA
GCTGATTGCCGGTCCATCCGTGTATATCTGCGACGAATGTGTTGATTTATGTAACGACATCATTCGCGAAGAGATTAAAG
AAGTTGCACCGCATCGTGAACGCAGTGCGCTACCGACGCCGCATGAAATTCGCAACCACCTGGACGATTACGTTATCGGT
CAGGAACAGGCGAAAAAAGTGCTGGCGGTCGCGGTATACAACCACTACAAACGTCTGCGCAACGGAGATACCAGCAATGG
CGTCGAGTTGGGCAAAAGTAACATTCTGCTGATCGGTCCGACCGGTTCCGGTAAAACGCTGCTGGCCGAAACGCTGGCGC
GCCTGCTGGACGTTCCGTTCACCATGGCTGACGCAACCACGCTGACCGAAGCCGGTTATGTGGGCGAAGACGTTGAAAAC
ATCATTCAGAAGCTGTTGCAGAAGTGCGATTACGACGTACAGAAAGCGCAGCGCGGGATTGTCTACATCGATGAAATCGA
CAAGATTTCTCGTAAGTCAGACAACCCGTCCATTACCCGAGACGTTTCCGGTGAAGGCGTACAGCAGGCACTGTTAAAAC
TGATCGAAGGTACGGTAGCTGCTGTTCCGCCGCAAGGTGGGCGTAAACATCCGCAGCAGGAATTCTTGCAGGTTGATACC
TCTAAGATCCTGTTCATCTGTGGCGGCGCATTTGCTGGCCTGGATAAAGTGATTGCCAATCGTGTTGAAACCGGCTCCGG
CATTGGTTTTGGCGCGACGGTGAAAGCCAAGTCCGACAAAGCCAGCGAAGGTGAACTGCTGGCGCAGGTTGAACCGGAAG
ATCTGATCAAGTTTGGTCTGATCCCTGAGTTCATTGGTCGTCTGCCGGTTGTCGCAACGTTGAATGAACTGAGCGAAGAA
GCTCTGATTCAGATCCTCAAAGAGCCGAAAAACGCCCTGACCAAGCAGTATCAGGCGCTGTTTAATCTGGAAGGCGTGGA
TCTGGAATTCCGTGACGAGGCGCTGGATGCTATCGCTAAGAAAGCGATGGCGCGTAAAACCGGTGCCCGTGGCCTGCGTT
CCATCGTAGAAGCCGCACTGCTCGATACCATGTACGATCTGCCGTCCATGGAAGATGTCGAAAAAGTGGTTATCGACGAG
TCGGTAATTGATGGTCAAAGCAAACCGTTGCTGATTTATGGTAAGCCGGAAGCGCAACAGGCATCTGGTGAATAA

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (112-310)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.85	94.575	0.566
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.392	96.226	0.533