Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M5R18_RS09690 Genome accession   NZ_CP103645
Coordinates   2002336..2002992 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 961     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1997336..2007992
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5R18_RS09660 (M5R18_09660) dcyD 1998216..1999202 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  M5R18_RS09665 (M5R18_09665) tcyL 1999217..1999885 (+) 669 WP_001158218.1 cystine ABC transporter permease -
  M5R18_RS09670 (M5R18_09670) tcyN 1999882..2000634 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  M5R18_RS09675 (M5R18_09675) sdiA 2000864..2001586 (+) 723 WP_106490481.1 transcriptional regulator SdiA -
  M5R18_RS09680 (M5R18_09680) yecF 2001653..2001877 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  M5R18_RS09685 (M5R18_09685) yecU 2001864..2002040 (-) 177 WP_001326718.1 protein YecU -
  M5R18_RS25625 - 2002123..2002194 (-) 72 Protein_1893 transcriptional regulator -
  M5R18_RS09690 (M5R18_09690) letA 2002336..2002992 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  M5R18_RS09695 (M5R18_09695) uvrC 2002989..2004821 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  M5R18_RS09700 (M5R18_09700) pgsA 2004878..2005426 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M5R18_RS09725 (M5R18_09725) - 2007227..2007535 (+) 309 Protein_1898 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=623965 M5R18_RS09690 WP_000611335.1 2002336..2002992(+) (letA) [Escherichia coli strain 961]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=623965 M5R18_RS09690 WP_000611335.1 2002336..2002992(+) (letA) [Escherichia coli strain 961]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486