Detailed information NTG0623489

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: M5S53_RS18485
• Genome accession: NZ_CP103592
• Coordinates: 3730786..3732060 (-)
• Length: 424 a.a.
• NCBI ID: WP_000130299.1
• Uniprot ID: -
• Organism: Escherichia coli O25b:H4-ST131 strain 4224
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3725786..3737060

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M5S53_RS18475 (M5S53_18475)	hupB	3727763..3728035 (-)	273	WP_001043542.1	nucleoid-associated protein HU-beta	-
M5S53_RS18480 (M5S53_18480)	lon	3728244..3730598 (-)	2355	WP_001295325.1	endopeptidase La	-
M5S53_RS18485 (M5S53_18485)	clpX	3730786..3732060 (-)	1275	WP_000130299.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
M5S53_RS18490 (M5S53_18490)	clpP	3732186..3732809 (-)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
M5S53_RS18495 (M5S53_18495)	tig	3733055..3734353 (-)	1299	WP_001198388.1	trigger factor	-
M5S53_RS18500 (M5S53_18500)	bolA	3734697..3735014 (-)	318	WP_000973448.1	transcriptional regulator BolA	-
M5S53_RS18505 (M5S53_18505)	yajG	3735319..3735897 (+)	579	WP_001295326.1	lipoprotein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46316.97 Da
• Isoelectric Point: 4.9297

>NTDB_id=623489 M5S53_RS18485 WP_000130299.1 3730786..3732060(-) (clpX) [Escherichia coli O25b:H4-ST131 strain 4224]
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIDGQSKPLLIYGKPEAQQASGE

Nucleotide

• Length: 1275 bp

>NTDB_id=623489 M5S53_RS18485 WP_000130299.1 3730786..3732060(-) (clpX) [Escherichia coli O25b:H4-ST131 strain 4224]
ATGACAGATAAACGCAAAGATGGCTCAGGCAAATTGCTGTATTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGCAA
GCTGATTGCCGGTCCATCCGTGTATATCTGCGACGAATGTGTTGATTTATGTAACGACATCATTCGCGAAGAGATTAAAG
AAGTTGCACCGCATCGTGAACGCAGTGCGCTACCGACGCCGCATGAAATTCGCAACCACCTGGACGATTACGTTATCGGT
CAGGAACAGGCGAAAAAAGTGCTGGCGGTCGCGGTATACAACCACTACAAACGTCTGCGCAACGGAGATACCAGCAATGG
CGTCGAGTTGGGCAAAAGTAACATTCTGCTGATCGGTCCGACCGGTTCCGGTAAAACGCTGCTGGCCGAAACGCTGGCGC
GCCTGCTGGACGTTCCGTTCACCATGGCTGACGCAACCACGCTGACCGAAGCCGGTTATGTGGGCGAAGACGTTGAAAAC
ATCATTCAGAAGCTGTTGCAGAAGTGCGATTACGACGTACAGAAAGCGCAGCGCGGGATTGTCTACATCGATGAAATCGA
CAAGATTTCTCGTAAGTCAGACAACCCGTCCATTACCCGAGACGTTTCCGGTGAAGGCGTACAGCAGGCACTGTTAAAAC
TGATCGAAGGTACGGTAGCTGCTGTTCCGCCGCAAGGTGGGCGTAAACATCCGCAGCAGGAATTCTTGCAGGTTGATACC
TCTAAGATCCTGTTCATCTGTGGCGGCGCATTTGCTGGCCTGGATAAAGTGATTGCCAATCGTGTTGAAACCGGCTCCGG
CATTGGTTTTGGCGCGACGGTGAAAGCCAAGTCCGACAAAGCCAGCGAAGGTGAACTGCTGGCGCAGGTTGAACCGGAAG
ATCTGATCAAGTTTGGTCTGATCCCTGAGTTCATTGGTCGTCTGCCGGTTGTCGCAACGTTGAATGAACTGAGCGAAGAA
GCTCTGATTCAGATCCTCAAAGAGCCGAAAAACGCCCTGACCAAGCAGTATCAGGCGCTGTTTAATCTGGAAGGCGTGGA
TCTGGAATTCCGTGACGAGGCGCTGGATGCTATCGCTAAGAAAGCGATGGCGCGTAAAACCGGTGCCCGTGGCCTGCGTT
CCATCGTAGAAGCCGCACTGCTCGATACCATGTACGATCTGCCGTCCATGGAAGATGTCGAAAAAGTGGTTATCGACGAG
TCGGTAATTGATGGTCAAAGCAAACCGTTGCTGATTTATGGTAAGCCGGAAGCGCAACAGGCATCTGGTGAATAA

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (112-310)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.85	94.575	0.566
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.392	96.226	0.533