Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M5S79_RS09415 Genome accession   NZ_CP103570
Coordinates   1959669..1960325 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 3045     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1954669..1965325
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5S79_RS09385 (M5S79_09385) dcyD 1955548..1956534 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  M5S79_RS09390 (M5S79_09390) tcyL 1956549..1957217 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  M5S79_RS09395 (M5S79_09395) tcyN 1957214..1957966 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  M5S79_RS09400 (M5S79_09400) sdiA 1958196..1958918 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  M5S79_RS09405 (M5S79_09405) yecF 1958986..1959210 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  M5S79_RS09410 (M5S79_09410) yecU 1959197..1959373 (-) 177 WP_000590344.1 protein YecU -
  M5S79_RS24595 - 1959411..1959527 (-) 117 WP_001302039.1 hypothetical protein -
  M5S79_RS09415 (M5S79_09415) letA 1959669..1960325 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  M5S79_RS09420 (M5S79_09420) uvrC 1960322..1962154 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  M5S79_RS09425 (M5S79_09425) pgsA 1962211..1962759 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M5S79_RS09445 (M5S79_09445) yecA 1963408..1964073 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=623301 M5S79_RS09415 WP_000611328.1 1959669..1960325(+) (letA) [Escherichia coli strain 3045]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=623301 M5S79_RS09415 WP_000611328.1 1959669..1960325(+) (letA) [Escherichia coli strain 3045]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482