Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M5T38_RS09685 Genome accession   NZ_CP103533
Coordinates   2014848..2015504 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 4238     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2009848..2020504
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5T38_RS09655 (M5T38_09655) dcyD 2010727..2011713 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  M5T38_RS09660 (M5T38_09660) tcyL 2011728..2012396 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  M5T38_RS09665 (M5T38_09665) tcyN 2012393..2013145 (+) 753 WP_032167552.1 L-cystine ABC transporter ATP-binding protein TcyN -
  M5T38_RS09670 (M5T38_09670) sdiA 2013375..2014097 (+) 723 WP_001154288.1 transcriptional regulator SdiA -
  M5T38_RS09675 (M5T38_09675) yecF 2014165..2014389 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  M5T38_RS09680 (M5T38_09680) yecU 2014376..2014552 (-) 177 WP_000590347.1 protein YecU -
  M5T38_RS09685 (M5T38_09685) letA 2014848..2015504 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  M5T38_RS09690 (M5T38_09690) uvrC 2015501..2017333 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  M5T38_RS09695 (M5T38_09695) pgsA 2017390..2017938 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M5T38_RS09715 (M5T38_09715) yecA 2018588..2019253 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=622807 M5T38_RS09685 WP_000611328.1 2014848..2015504(+) (letA) [Escherichia coli strain 4238]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=622807 M5T38_RS09685 WP_000611328.1 2014848..2015504(+) (letA) [Escherichia coli strain 4238]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482