Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   KW2_RS07710 Genome accession   NC_022369
Coordinates   1635749..1637221 (-) Length   490 a.a.
NCBI ID   WP_021037558.1    Uniprot ID   -
Organism   Lactococcus cremoris subsp. cremoris KW2     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1630749..1642221
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KW2_RS07690 (kw2_1544) murG 1631065..1632138 (-) 1074 WP_021037555.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  KW2_RS07695 (kw2_1545) murD 1632380..1633729 (-) 1350 WP_021037556.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  KW2_RS07700 (kw2_1546) - 1633898..1634239 (-) 342 WP_011676628.1 P-II family nitrogen regulator -
  KW2_RS07705 (kw2_1547) - 1634322..1635563 (-) 1242 WP_021037557.1 ammonium transporter -
  KW2_RS07710 (kw2_1548) covS 1635749..1637221 (-) 1473 WP_021037558.1 HAMP domain-containing sensor histidine kinase Regulator
  KW2_RS07715 (kw2_1549) covR 1637234..1637926 (-) 693 WP_011676631.1 response regulator transcription factor Regulator
  KW2_RS07720 (kw2_1550) - 1638083..1638613 (-) 531 WP_021037559.1 YceD family protein -
  KW2_RS07725 (kw2_1551) - 1638746..1638991 (-) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  KW2_RS07730 (kw2_1552) - 1639315..1639677 (-) 363 WP_021037560.1 TIGR02328 family protein -
  KW2_RS07735 (kw2_1553) - 1639914..1640825 (-) 912 WP_021037561.1 CHAP domain-containing protein -
  KW2_RS07740 (kw2_1554) - 1640918..1641754 (-) 837 WP_021037562.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55890.74 Da        Isoelectric Point: 4.7011

>NTDB_id=62271 KW2_RS07710 WP_021037558.1 1635749..1637221(-) (covS) [Lactococcus cremoris subsp. cremoris KW2]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKM

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=62271 KW2_RS07710 WP_021037558.1 1635749..1637221(-) (covS) [Lactococcus cremoris subsp. cremoris KW2]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATTAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTATTATATTCAACTAATCGACATGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGTGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTAGCCAGACTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTACTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTTGCTCGTTTAGCCGAAAATTATCAAGGGGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATGTGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

HAMP domain (HAMP)

(208-258)

ArlS sensor domain (ArlS_N)

(54-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.694

100

0.947

Multiple sequence alignment