Detailed information NTG0062272

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: GOZ34_RS12760
• Genome accession: NZ_AP019712
• Coordinates: 2583591..2585699 (+)
• Length: 702 a.a.
• NCBI ID: WP_155978329.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain Tokyo12480
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2578591..2590699

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOZ34_RS12735 (TMSFP480_24020)	-	2578612..2578830 (+)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-
GOZ34_RS12740 (TMSFP480_24030)	-	2579218..2579649 (+)	432	WP_000875614.1	CHAP domain-containing protein	-
GOZ34_RS12745 (TMSFP480_24040)	-	2579789..2581069 (-)	1281	WP_001191004.1	hydroxymethylglutaryl-CoA reductase, degradative	-
GOZ34_RS12750 (TMSFP480_24050)	-	2581324..2582490 (+)	1167	WP_000151981.1	hydroxymethylglutaryl-CoA synthase	-
GOZ34_RS12755 (TMSFP480_24060)	-	2582661..2583182 (-)	522	WP_000384652.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
GOZ34_RS12760 (TMSFP480_24070)	clpE	2583591..2585699 (+)	2109	WP_155978329.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
GOZ34_RS12765 (TMSFP480_24080)	-	2585766..2585936 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
GOZ34_RS12770 (TMSFP480_24090)	feoB	2585949..2587943 (-)	1995	WP_155978330.1	ferrous iron transport protein B	-
GOZ34_RS12775 (TMSFP480_24100)	-	2587955..2588182 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 77971.38 Da
• Isoelectric Point: 4.6037

>NTDB_id=62272 GOZ34_RS12760 WP_155978329.1 2583591..2585699(+) (clpE) [Staphylococcus aureus strain Tokyo12480]
MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDAEEKDIMQEMKKFFRPEFLNRFNGIVEFIHLDKESLQDIVNLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=62272 GOZ34_RS12760 WP_155978329.1 2583591..2585699(+) (clpE) [Staphylococcus aureus strain Tokyo12480]
ATGAATAACGGTTTTTTCAATAGCGACTTTGATTCAATTTTTCGAAGAATGATGCAAGATATGCAAGGTTCAAATCAAGT
CGGTAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGGCAACAAGGTGGTAACGGCAATTAT
TTAGAACAAATTGGCCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAAT
TCAAGAAACTGCTGAAGTTTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCACAGGCAATCGTTGAAGGGAATGTACCTGCAGCCATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAA
ATCTTCACAAAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAGATTTCTATTATTGGTGCAACAACACAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAGTGCTAAAGA
TACTGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTCAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCCATTCAATATATTCCACAACGCCTATTACCTGACAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ATAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCACGTGCAATTCGCCGTAATCGTGCTGGGTTTGATGACGGAAACCGCCCAATTGGCAGTTTCC
TATTTGTTGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTGATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGATGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGCAATGACGCTGAAGAAAAAGACATTAT
GCAAGAAATGAAAAAATTCTTCCGTCCTGAATTCCTTAACCGTTTCAATGGTATTGTGGAATTCATACACCTAGATAAAG
AGTCACTACAAGATATCGTCAACTTATTATTAGACGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAGGGATATGATGAAGAGTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (264-363)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.523	91.595	0.444
clpE	Streptococcus pneumoniae Rx1	47.974	87.892	0.422
clpE	Streptococcus pneumoniae D39	47.974	87.892	0.422
clpE	Streptococcus pneumoniae R6	47.974	87.892	0.422
clpE	Streptococcus pneumoniae TIGR4	47.974	87.892	0.422
clpC	Lactococcus lactis subsp. cremoris KW2	46.677	90.028	0.42
clpC	Bacillus subtilis subsp. subtilis str. 168	44.564	93.02	0.415
clpC	Streptococcus thermophilus LMD-9	44.55	90.171	0.402
clpC	Streptococcus thermophilus LMG 18311	44.234	90.171	0.399
clpC	Streptococcus pneumoniae TIGR4	44.013	88.034	0.387
clpC	Streptococcus pneumoniae Rx1	44.013	88.034	0.387
clpC	Streptococcus pneumoniae D39	44.013	88.034	0.387
clpC	Streptococcus mutans UA159	43.74	87.607	0.383
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.294	92.45	0.382