Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M5S50_RS10080 Genome accession   NZ_CP103468
Coordinates   2138615..2139271 (+) Length   218 a.a.
NCBI ID   WP_022645829.1    Uniprot ID   -
Organism   Escherichia coli strain 4973     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2133615..2144271
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5S50_RS10050 (M5S50_10050) dcyD 2134495..2135481 (+) 987 WP_001128235.1 D-cysteine desulfhydrase -
  M5S50_RS10055 (M5S50_10055) tcyL 2135496..2136164 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  M5S50_RS10060 (M5S50_10060) tcyN 2136161..2136913 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  M5S50_RS10065 (M5S50_10065) sdiA 2137143..2137865 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  M5S50_RS10070 (M5S50_10070) yecF 2137932..2138156 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  M5S50_RS10075 (M5S50_10075) yecU 2138143..2138319 (-) 177 WP_001307856.1 protein YecU -
  M5S50_RS10080 (M5S50_10080) letA 2138615..2139271 (+) 657 WP_022645829.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  M5S50_RS10085 (M5S50_10085) uvrC 2139268..2141100 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  M5S50_RS10090 (M5S50_10090) pgsA 2141157..2141705 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M5S50_RS10110 (M5S50_10110) - 2142403..2143044 (-) 642 Protein_1982 hypothetical protein -
  M5S50_RS10115 (M5S50_10115) - 2143117..2144205 (+) 1089 Protein_1983 IS3 family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23938.73 Da        Isoelectric Point: 6.9612

>NTDB_id=622306 M5S50_RS10080 WP_022645829.1 2138615..2139271(+) (letA) [Escherichia coli strain 4973]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIAYDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=622306 M5S50_RS10080 WP_022645829.1 2138615..2139271(+) (letA) [Escherichia coli strain 4973]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTATGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482