Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   NW971_RS08740 Genome accession   NZ_CP102962
Coordinates   1772331..1773593 (-) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain 16CS0212     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1767331..1778593
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW971_RS08715 (NW971_08715) - 1767529..1768197 (-) 669 WP_000805942.1 uroporphyrinogen-III synthase -
  NW971_RS08720 (NW971_08720) hemC 1768219..1769145 (-) 927 WP_001230225.1 hydroxymethylbilane synthase -
  NW971_RS08725 (NW971_08725) - 1769187..1770002 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  NW971_RS08730 (NW971_08730) hemA 1770024..1771370 (-) 1347 WP_000545460.1 glutamyl-tRNA reductase -
  NW971_RS08735 (NW971_08735) yihA 1771587..1772177 (-) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  NW971_RS08740 (NW971_08740) clpX 1772331..1773593 (-) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  NW971_RS08745 (NW971_08745) tig 1773744..1775045 (-) 1302 WP_000127572.1 trigger factor -
  NW971_RS08750 (NW971_08750) - 1775093..1775203 (-) 111 WP_001790560.1 hypothetical protein -
  NW971_RS08755 (NW971_08755) - 1775208..1776137 (-) 930 WP_001280020.1 hypothetical protein -
  NW971_RS08760 (NW971_08760) - 1776156..1776764 (-) 609 WP_000032657.1 NUDIX domain-containing protein -
  NW971_RS08765 (NW971_08765) rplT 1776906..1777262 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  NW971_RS08770 (NW971_08770) rpmI 1777309..1777509 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  NW971_RS08775 (NW971_08775) infC 1777538..1778065 (-) 528 WP_001791162.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=619910 NW971_RS08740 WP_000472293.1 1772331..1773593(-) (clpX) [Staphylococcus aureus strain 16CS0212]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=619910 NW971_RS08740 WP_000472293.1 1772331..1773593(-) (clpX) [Staphylococcus aureus strain 16CS0212]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTTGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCCTTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCCCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACAACTGCGAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACGGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531