Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   NWO26_RS07565 Genome accession   NZ_CP102797
Coordinates   1467618..1469561 (+) Length   647 a.a.
NCBI ID   WP_113870458.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST057-1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1462618..1474561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWO26_RS07535 argR 1462822..1463250 (+) 429 WP_024704313.1 arginine repressor -
  NWO26_RS07540 - 1463250..1463609 (+) 360 WP_011225277.1 YlbF family regulator -
  NWO26_RS07545 hexA 1463602..1466160 (+) 2559 WP_011680597.1 DNA mismatch repair protein MutS Machinery gene
  NWO26_RS07550 - 1466194..1466649 (-) 456 WP_011680598.1 DUF3021 domain-containing protein -
  NWO26_RS07555 - 1466646..1467037 (-) 392 Protein_1467 LytTR family DNA-binding domain-containing protein -
  NWO26_RS07560 - 1467261..1467566 (+) 306 WP_014621013.1 hypothetical protein -
  NWO26_RS07565 hexB 1467618..1469561 (+) 1944 WP_113870458.1 DNA mismatch repair endonuclease MutL Machinery gene
  NWO26_RS07570 - 1469691..1469912 (+) 222 WP_011680602.1 hypothetical protein -
  NWO26_RS07575 ruvA 1470064..1470654 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA Machinery gene
  NWO26_RS07580 - 1470661..1471215 (+) 555 WP_014621014.1 DNA-3-methyladenine glycosylase I -
  NWO26_RS07585 cinA 1471311..1472582 (+) 1272 WP_014621015.1 competence/damage-inducible protein A Machinery gene
  NWO26_RS07590 recA 1472618..1473757 (+) 1140 WP_011680606.1 recombinase RecA Machinery gene
  NWO26_RS07595 spx 1473934..1474332 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72420.65 Da        Isoelectric Point: 6.1297

>NTDB_id=618323 NWO26_RS07565 WP_113870458.1 1467618..1469561(+) (hexB) [Streptococcus thermophilus strain ST057-1]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAAGGEVYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALIKS
AIAQSLREQDLIPDALENLAKSSTRGATRSVQTSLPLKQTNLYYDSSRNDFFVTPETVQEDIKPLVSKSESSVSSVANKQ
QPTVKQAKRSADDSDSEHGKLDYKNKSKLKRMLENLTNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKY
EYYREKIGVVDSSLQQLLVPYLFEFSGSDYISLQEKMPLLNQVCIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRDLGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=618323 NWO26_RS07565 WP_113870458.1 1467618..1469561(+) (hexB) [Streptococcus thermophilus strain ST057-1]
ATGCCAAAAATTATCGAATTGCCTGAAGTTCTAGCCAATCAGATTGCTGCTGGTGAGGTCGTAGAGCGACCAGCTAGTGT
AGTTAAAGAGCTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACTATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATCACAGACAATGGCGAAGGAATGGCTCAAGCTGATGTAGCTATGAGTTTGCGCCGTCATGCAACGAGTAAA
ATCAAAAATCAAGGAGATCTCTTTCGTATTCGAACACTTGGTTTTCGAGGTGAAGCCCTACCCTCTATAGCTTCTATTAG
TCACCTTACCATTGTGACAGCAGCGGGTGGAGAAGTCTATGGGACCAAACTTGTTGCTAAAGGTGGAGAAATTGAGAGTC
AAGATCCTATTTCAACCCCAGTGGGAACAAAGATTACAGTTGAAAACTTGTTTTATAATACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTCGATGTTGTCAACCGTTTGAGTTTAGCCCACCCCGAAGTAGCCTT
CACCTTGCTTAATGACGGTCGTCAGTTGACACAGACATCAGGTACTGGAGACCTTCGCCAAGCTATTGCAGGGATTTATG
GCTTAACAACAGCAAAAAAAATGGTGGAAATTTCAAATTCCGACCTTGATTTTGAAGTTTCTGGTTATGTCAGTCTCCCT
GAATTAACGCGTGCTAACCGTAACTATATCACGATTCTTATTAACGGACGCTATATAAAAAACTTCCTCCTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTTATGGTGGGACGCTTCCCAATTGCAGTTATTGATATTCAGATTGATCCTTATT
TGGCAGATGTCAATGTTCACCCAACAAAGCAAGAAGTACGTATCTCTAAAGAAAAGGAGCTCATGGCCCTTATCAAATCT
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCAAAGTCAAGTACTAGAGGTGC
AACTAGGTCAGTTCAGACGAGTCTCCCACTCAAACAAACCAATCTTTACTATGACAGTAGCCGTAATGATTTCTTTGTCA
CGCCAGAGACAGTTCAAGAGGATATCAAACCTCTTGTATCAAAGTCAGAGTCTTCAGTTTCATCGGTAGCAAACAAACAG
CAACCTACTGTTAAACAGGCAAAACGTTCAGCAGATGATAGTGATAGCGAACACGGAAAACTTGACTATAAAAATAAATC
GAAATTGAAGCGCATGCTTGAAAATCTGACCAATGAGGAAACATCAACCTTTCCTGAATTGGAGTTCTTTGGTCAAATGC
ATGGAACCTACCTCTTTGCCCAAGGACAAGGTGGCCTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTAT
GAGTACTATCGCGAAAAGATAGGTGTGGTTGATAGTAGTTTACAACAACTTTTGGTTCCCTATCTTTTTGAATTTTCAGG
TTCAGATTACATTAGTTTACAAGAAAAAATGCCTCTTCTTAACCAAGTTTGCATCTATTTGGAGCCTTATGGGAATAATA
CCTTCATTCTTCGAGAGCACCCTATCTGGATGAAGGAAGAAGAAATCGAATCTGCAGTCTATGAGATGTGTGATATGCTT
CTTTTGACGAACGAAGTATCCGTCAAGACCTATCGTGCTGAGTTAGCCATCATGATGAGTTGTAAACGTTCAATAAAGGC
CAATCATGCTCTTGATGATTACTCTGCGCGTGACCTTCTAGTACAGCTTGCACAGTGCAAAAATCCCTATAATTGTCCTC
ACGGCCGTCCAGTACTTGTCAACTTTACCAAGTCTGATATGGAAAAAATGTTCCGTCGTATTCAAGAAAACCATACCAGC
CTACGTGATTTAGGAAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-123)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(448-591)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.95

100

0.7