Detailed information NTG0061801

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: SCR2_RS01465
• Genome accession: NC_022245
• Coordinates: 279629..280111 (+)
• Length: 160 a.a.
• NCBI ID: WP_006267672.1
• Uniprot ID: A0A380L5Q1
• Organism: Streptococcus constellatus subsp. pharyngis C818
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 274629..285111

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCR2_RS01440 (SCR2_0282)	-	275902..276656 (-)	755	Protein_268	hypothetical protein	-
SCR2_RS01445 (SCR2_0283)	-	276815..277876 (+)	1062	WP_006269276.1	M24 family metallopeptidase	-
SCR2_RS01450 (SCR2_0284)	efp	277935..278495 (+)	561	WP_003026309.1	elongation factor P	-
SCR2_RS01455 (SCR2_0285)	-	278606..278995 (+)	390	WP_006269324.1	Asp23/Gls24 family envelope stress response protein	-
SCR2_RS01460 (SCR2_0286)	nusB	278988..279413 (+)	426	WP_003037723.1	transcription antitermination factor NusB	-
SCR2_RS01465 (SCR2_0287)	comR/comR2	279629..280111 (+)	483	WP_006267672.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 160 a.a.
• Molecular weight: 19855.70 Da
• Isoelectric Point: 7.9710

>NTDB_id=61801 SCR2_RS01465 WP_006267672.1 279629..280111(+) (comR/comR2) [Streptococcus constellatus subsp. pharyngis C818]
MDFKELYDKVRGIVLKCRREYYVHLWELSDWDQEGMLVLYELVSRYPQLVESESRLYVYYKTKFRNHIKDILRKQESQKR
KLDRQVYEEVSEIGHKLSLKELYLDELVILRDQLKSYQKQLSPEKQEQYERLLADERFQGRQAMLRELRTYLQDYDERKS

Nucleotide

• Length: 483 bp

>NTDB_id=61801 SCR2_RS01465 WP_006267672.1 279629..280111(+) (comR/comR2) [Streptococcus constellatus subsp. pharyngis C818]
ATGGACTTCAAGGAATTGTATGACAAAGTGAGAGGGATCGTACTGAAGTGTCGCCGGGAATATTATGTCCACCTGTGGGA
GTTAAGTGATTGGGACCAAGAAGGGATGCTGGTCTTATATGAGTTGGTGAGTCGCTATCCGCAACTGGTAGAGTCAGAAA
GTCGTCTCTATGTTTACTATAAGACCAAGTTCCGTAATCACATCAAGGACATCCTGCGCAAACAAGAAAGCCAAAAGCGC
AAACTAGACCGTCAAGTCTATGAGGAAGTGAGCGAGATAGGTCACAAGCTCAGCCTGAAAGAACTCTATTTGGATGAATT
GGTGATTCTCCGAGACCAACTAAAGAGCTATCAAAAACAGCTAAGTCCAGAGAAACAAGAACAGTATGAGCGCTTACTAG
CAGATGAACGGTTTCAAGGACGCCAAGCGATGCTTCGGGAGTTACGGACCTACTTACAAGATTACGATGAAAGAAAAAGC
TAG

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A380L5Q1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	61.392	98.75	0.606
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	61.392	98.75	0.606
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	56.41	97.5	0.55
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	55.128	97.5	0.537
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	55.128	97.5	0.537
comX/comX1	Streptococcus pneumoniae R6	55.556	95.625	0.531
comX/comX1	Streptococcus pneumoniae D39	55.556	95.625	0.531
comX/comX2	Streptococcus pneumoniae Rx1	55.556	95.625	0.531
comX/comX1	Streptococcus pneumoniae Rx1	55.556	95.625	0.531
comX/comX2	Streptococcus pneumoniae D39	55.556	95.625	0.531
comX/comX2	Streptococcus pneumoniae R6	55.556	95.625	0.531
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	54.487	97.5	0.531
comX/comX2	Streptococcus pneumoniae TIGR4	54.902	95.625	0.525
comX/comX1	Streptococcus pneumoniae TIGR4	54.902	95.625	0.525
comX/sigX	Streptococcus mutans UA159	50.318	98.125	0.494
comX/sigX	Streptococcus suis D9	46.452	96.875	0.45
comX/sigX	Streptococcus suis isolate S10	46.452	96.875	0.45
comX/sigX	Streptococcus suis P1/7	46.452	96.875	0.45
comX	Streptococcus salivarius SK126	43.506	96.25	0.419
comX/sigX	Streptococcus salivarius strain HSISS4	42.857	96.25	0.412
comX	Streptococcus thermophilus LMG 18311	42.857	96.25	0.412
comX	Streptococcus thermophilus LMD-9	42.857	96.25	0.412
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40.764	98.125	0.4
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40.764	98.125	0.4
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	40.764	98.125	0.4
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	40.764	98.125	0.4
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40.764	98.125	0.4
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40.764	98.125	0.4
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	39.744	97.5	0.388
comX	Streptococcus sobrinus strain NIDR 6715-7	37.419	96.875	0.362