Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NU949_RS10535 Genome accession   NZ_CP102679
Coordinates   1722608..1723264 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain XH989     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1717608..1728264
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NU949_RS10505 (NU949_10505) dcyD 1718488..1719474 (+) 987 WP_001128213.1 D-cysteine desulfhydrase -
  NU949_RS10510 (NU949_10510) tcyL 1719489..1720157 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NU949_RS10515 (NU949_10515) tcyN 1720154..1720906 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NU949_RS10520 (NU949_10520) sdiA 1721136..1721858 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  NU949_RS10525 (NU949_10525) yecF 1721925..1722149 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NU949_RS10530 (NU949_10530) yecU 1722136..1722312 (-) 177 WP_001307856.1 protein YecU -
  NU949_RS26225 - 1722395..1722466 (-) 72 Protein_1662 transcriptional regulator -
  NU949_RS10535 (NU949_10535) letA 1722608..1723264 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NU949_RS10540 (NU949_10540) uvrC 1723261..1725093 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  NU949_RS10545 (NU949_10545) pgsA 1725150..1725698 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NU949_RS10565 (NU949_10565) yecA 1726348..1727013 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=617688 NU949_RS10535 WP_000611328.1 1722608..1723264(+) (letA) [Escherichia coli strain XH989]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=617688 NU949_RS10535 WP_000611328.1 1722608..1723264(+) (letA) [Escherichia coli strain XH989]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482