Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NU950_RS25445 Genome accession   NZ_CP102675
Coordinates   4817766..4818422 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain XH987     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4812766..4823422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NU950_RS25415 (NU950_25415) dcyD 4813646..4814632 (+) 987 WP_001128213.1 D-cysteine desulfhydrase -
  NU950_RS25420 (NU950_25420) tcyL 4814647..4815315 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NU950_RS25425 (NU950_25425) tcyN 4815312..4816064 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NU950_RS25430 (NU950_25430) sdiA 4816294..4817016 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  NU950_RS25435 (NU950_25435) yecF 4817083..4817307 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NU950_RS25440 (NU950_25440) yecU 4817294..4817470 (-) 177 WP_001307856.1 protein YecU -
  NU950_RS26170 - 4817553..4817624 (-) 72 Protein_4612 transcriptional regulator -
  NU950_RS25445 (NU950_25445) letA 4817766..4818422 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NU950_RS25450 (NU950_25450) uvrC 4818419..4820251 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  NU950_RS25455 (NU950_25455) pgsA 4820308..4820856 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NU950_RS25475 (NU950_25475) yecA 4821506..4822171 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=617655 NU950_RS25445 WP_000611328.1 4817766..4818422(+) (letA) [Escherichia coli strain XH987]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=617655 NU950_RS25445 WP_000611328.1 4817766..4818422(+) (letA) [Escherichia coli strain XH987]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482