Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   LIN44_RS12320 Genome accession   NZ_CP085344
Coordinates   2669574..2672006 (-) Length   810 a.a.
NCBI ID   WP_227312318.1    Uniprot ID   -
Organism   Cupriavidus sp. MP-37     
Function   DNA uptake (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2664574..2677006
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIN44_RS12305 (LIN44_12305) - 2665801..2666307 (-) 507 WP_227314393.1 gluconokinase -
  LIN44_RS12310 (LIN44_12310) edd 2666473..2668365 (-) 1893 WP_227312316.1 phosphogluconate dehydratase -
  LIN44_RS12315 (LIN44_12315) - 2668634..2669551 (+) 918 WP_227312317.1 MurR/RpiR family transcriptional regulator -
  LIN44_RS12320 (LIN44_12320) comA 2669574..2672006 (-) 2433 WP_227312318.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LIN44_RS12325 (LIN44_12325) - 2672079..2672939 (-) 861 WP_227312319.1 TatD family hydrolase -
  LIN44_RS12330 (LIN44_12330) lolD 2672953..2673693 (-) 741 WP_227312320.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  LIN44_RS12335 (LIN44_12335) - 2673686..2674936 (-) 1251 WP_227312321.1 lipoprotein-releasing ABC transporter permease subunit -
  LIN44_RS12340 (LIN44_12340) - 2675095..2676210 (+) 1116 WP_227312322.1 hypothetical protein -

Sequence

Protein


Download         Length: 810 a.a.        Molecular weight: 86326.93 Da        Isoelectric Point: 11.2387

>NTDB_id=617234 LIN44_RS12320 WP_227312318.1 2669574..2672006(-) (comA) [Cupriavidus sp. MP-37]
MRRFVVAFVAGCWTLQQQATLPQPPGLRLGAALLALCAIGVALWRRRLPAMLQGLALAMLAFAIAFCWAAWRAEQRLREW
LPVALEARDLDVRGVVSGLPTQTATGTRFAFTVEQSAEPDLPLPGRVILNWRDAPPDLSPGQRFTLTLRLRRPRGLANPF
AFDYAYWLLAQGYGATGYVRRAQGPPQDAASERLAWRIEAWRAAVRDRLRAALPAGARYGAVLVALVIGDQRAIGAEDWQ
LFRRTGVSHLVAISGLHITMVAGMAASLAGLLWRHSFGCGRWLRRPLPLWLPARQAALAMAVATALDYGMLAGMQIPALR
TVAMLCVAAVAVWGARAPPASVVLAWAALVALLVDPWAVMLPGFWLSFGAVAVIFFAARPGRDAAIAGRWPRLRATLAAG
ARTQWAVTIGLVPLTLLLFGQVSVVSPLANAVAIPVVSLLVTPLALLCAALPVVLAAPVMAVAHFAMVGLAAVLEWLSML
PWAMWEAASAGPVALMLAALGVAVLVAPVASARLRRHGVLLMLPMLLARGPPVADGQFRAVMFDVGQGTAVLVRTRAHAL
VYDAGPGYATGASAGAQVVVPRLRAEGVTRLDHLMVSHEDIDHAGGVADVVGAVAVAARSTGAPAGHLLLGGRQPGATPG
QWPPCAAGQQWEWDGVRFSVLHPLPEEAQLAAIPSNARSCVLRVDTGAHSLLLTGDIGRAQERALIERLPAGALRADVLV
VAHHGSGTSSGADWIEAVGPAAAVFQLGYGNRYRHPNAEVWERFGRSGISRYRTDETGAVTLDTARAGYTLSMFRQAEPR
YWRERPPAPR

Nucleotide


Download         Length: 2433 bp        

>NTDB_id=617234 LIN44_RS12320 WP_227312318.1 2669574..2672006(-) (comA) [Cupriavidus sp. MP-37]
GTGCGTCGCTTCGTGGTGGCATTCGTGGCCGGGTGCTGGACCCTGCAGCAGCAAGCGACGCTGCCGCAGCCGCCCGGGCT
GCGCCTGGGCGCCGCGCTGCTGGCGTTGTGCGCCATCGGCGTGGCCCTGTGGCGCAGGCGCCTGCCTGCCATGCTGCAAG
GCCTGGCGCTGGCGATGCTGGCCTTTGCCATTGCGTTCTGCTGGGCCGCCTGGCGCGCCGAGCAGCGCCTGCGCGAATGG
CTGCCGGTGGCGCTGGAAGCCCGTGACCTTGACGTGCGCGGCGTGGTTTCCGGCCTGCCCACCCAGACCGCCACCGGCAC
GCGTTTCGCGTTCACCGTCGAGCAGTCAGCCGAGCCGGATCTGCCGCTGCCCGGCCGGGTCATCCTCAACTGGCGCGACG
CGCCGCCCGACCTGAGCCCGGGGCAGCGCTTCACGCTGACCTTGCGCCTGCGGCGCCCGCGCGGGCTCGCCAATCCGTTC
GCCTTCGACTACGCCTACTGGCTGCTGGCACAAGGCTATGGCGCGACCGGCTACGTGCGCCGCGCCCAGGGCCCGCCGCA
GGACGCGGCATCCGAGCGGCTGGCCTGGCGCATCGAAGCCTGGCGTGCCGCGGTGCGCGACCGCCTGCGCGCCGCGCTGC
CGGCCGGGGCGCGCTACGGCGCCGTGCTGGTCGCGCTGGTGATCGGCGACCAGCGCGCCATCGGGGCGGAGGACTGGCAG
CTGTTCCGGCGCACGGGCGTGAGCCACCTGGTGGCCATTTCGGGGCTGCATATCACCATGGTGGCCGGCATGGCGGCGTC
GCTCGCCGGACTGTTGTGGCGCCATTCGTTCGGCTGCGGCCGCTGGCTGCGCCGGCCGCTGCCACTGTGGCTGCCGGCCC
GGCAAGCCGCGCTGGCGATGGCCGTGGCCACCGCGCTGGACTACGGCATGCTGGCCGGCATGCAGATCCCGGCGCTGCGC
ACCGTCGCCATGCTGTGCGTCGCGGCAGTCGCGGTATGGGGGGCACGCGCGCCGCCGGCGTCGGTGGTGCTGGCATGGGC
AGCGCTGGTGGCGCTGCTGGTGGACCCGTGGGCGGTGATGCTGCCGGGCTTCTGGCTGTCCTTCGGCGCCGTCGCGGTGA
TCTTTTTCGCCGCCCGTCCCGGACGCGACGCCGCGATCGCGGGGCGCTGGCCACGGCTGCGGGCCACGCTCGCCGCGGGG
GCGCGCACCCAGTGGGCTGTCACCATCGGGCTGGTGCCGCTGACGCTGCTGCTGTTCGGCCAGGTCTCGGTGGTGTCGCC
GCTTGCCAATGCGGTGGCGATTCCGGTGGTCAGCCTGCTGGTGACGCCGCTGGCACTGCTGTGCGCCGCGCTGCCCGTGG
TGCTTGCCGCGCCGGTCATGGCAGTCGCCCACTTTGCGATGGTGGGGCTGGCTGCCGTGCTCGAATGGCTCTCCATGCTG
CCCTGGGCGATGTGGGAAGCCGCCAGCGCCGGGCCAGTGGCGCTAATGCTGGCTGCGCTTGGCGTGGCAGTGCTGGTGGC
GCCCGTGGCTTCGGCGCGCCTGCGCCGGCATGGCGTGCTGCTGATGCTGCCGATGCTGCTGGCGCGCGGCCCGCCGGTCG
CAGACGGCCAGTTCCGCGCGGTGATGTTCGACGTGGGGCAGGGCACGGCGGTGCTGGTGCGCACGCGCGCGCACGCGCTG
GTGTACGACGCCGGGCCGGGCTATGCCACGGGCGCCAGCGCGGGCGCGCAGGTGGTGGTGCCGCGATTGCGCGCCGAGGG
GGTGACGCGGCTCGATCACCTGATGGTCAGCCATGAAGACATCGACCATGCCGGCGGCGTGGCCGACGTTGTCGGGGCGG
TGGCCGTGGCGGCGCGCAGCACCGGTGCACCTGCCGGTCACTTGCTGCTCGGTGGCCGGCAGCCCGGGGCCACGCCGGGC
CAATGGCCGCCATGCGCGGCCGGTCAGCAATGGGAGTGGGACGGCGTGCGTTTTTCCGTGCTGCATCCGTTGCCTGAGGA
AGCCCAGCTGGCCGCCATCCCCAGCAATGCGCGCAGTTGCGTGCTGCGCGTCGACACGGGCGCGCACAGCCTGCTGCTGA
CCGGCGATATCGGCCGGGCGCAGGAGCGTGCGTTGATCGAGCGCCTGCCGGCCGGGGCTTTGCGTGCGGACGTGCTGGTG
GTGGCGCATCACGGCAGCGGCACCTCGTCCGGCGCCGACTGGATCGAGGCGGTCGGGCCAGCGGCCGCGGTGTTCCAGCT
CGGCTATGGCAACCGCTATCGCCATCCGAACGCCGAAGTCTGGGAGCGTTTTGGCCGCTCGGGCATCTCGCGCTATCGCA
CTGACGAAACCGGCGCGGTGACCCTGGACACGGCGCGCGCGGGTTACACGCTGTCGATGTTCCGGCAGGCCGAGCCGCGC
TACTGGCGGGAACGGCCGCCGGCGCCGCGCTAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(545-744)

Competence protein (Competence)

(226-507)

Domain of unknown function (DUF4131) (DUF4131)

(23-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Ralstonia pseudosolanacearum GMI1000

47.375

100

0.49
  comA Pseudomonas stutzeri DSM 10701

39.052

96.42

0.377