Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   NUU05_RS01655 Genome accession   NZ_CP102538
Coordinates   296621..296914 (+) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain TH-4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 291621..301914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NUU05_RS01630 (NUU05_01620) - 293572..293934 (+) 363 WP_011226630.1 DUF1033 family protein -
  NUU05_RS01635 (NUU05_01625) comGA/cglA/cilD 294015..294956 (+) 942 WP_011681689.1 competence type IV pilus ATPase ComGA Machinery gene
  NUU05_RS01640 (NUU05_01630) comGB 294838..295938 (+) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  NUU05_RS01645 (NUU05_01635) comGC 295935..296261 (+) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  NUU05_RS01650 (NUU05_01640) comGD 296221..296649 (+) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  NUU05_RS01655 (NUU05_01645) comGE 296621..296914 (+) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  NUU05_RS01660 (NUU05_01650) comGF 296898..297335 (+) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  NUU05_RS01665 (NUU05_01655) comGG 297313..297630 (+) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG Machinery gene
  NUU05_RS01670 (NUU05_01660) comGH 297675..298631 (+) 957 WP_011681684.1 class I SAM-dependent methyltransferase Machinery gene
  NUU05_RS01675 (NUU05_01665) - 298687..299880 (+) 1194 WP_014608740.1 acetate kinase -
  NUU05_RS01680 (NUU05_01670) - 300129..300326 (+) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  NUU05_RS01685 (NUU05_01675) - 300338..300613 (+) 276 WP_011681681.1 hypothetical protein -
  NUU05_RS01690 (NUU05_01680) - 300657..300995 (+) 339 WP_224103197.1 CPBP family intramembrane glutamic endopeptidase -
  NUU05_RS01695 (NUU05_01685) - 301069..301512 (+) 444 WP_011681680.1 hypothetical protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=617081 NUU05_RS01655 WP_011226625.1 296621..296914(+) (comGE) [Streptococcus thermophilus strain TH-4]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=617081 NUU05_RS01655 WP_011226625.1 296621..296914(+) (comGE) [Streptococcus thermophilus strain TH-4]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361