Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SANR_RS10375 Genome accession   NC_022239
Coordinates   2122544..2123812 (-) Length   422 a.a.
NCBI ID   WP_003038347.1    Uniprot ID   I0S7M7
Organism   Streptococcus anginosus C238     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2117544..2128812
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SANR_RS10340 (SANR_2009) - 2118388..2118699 (-) 312 WP_003027765.1 DUF1292 domain-containing protein -
  SANR_RS10345 (SANR_2010) ruvX 2118717..2119136 (-) 420 WP_003038407.1 Holliday junction resolvase RuvX -
  SANR_RS10350 (SANR_2011) - 2119136..2119402 (-) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  SANR_RS10355 (SANR_2012) - 2119683..2120174 (-) 492 WP_025271567.1 SP0191 family lipoprotein -
  SANR_RS10360 (SANR_2013) - 2120278..2120730 (-) 453 WP_003038334.1 SP0191 family lipoprotein -
  SANR_RS12265 - 2120700..2120780 (-) 81 WP_229031567.1 lipoprotein -
  SANR_RS10365 (SANR_2014) spx 2120866..2121264 (-) 399 WP_003026638.1 transcriptional regulator Spx -
  SANR_RS10370 (SANR_2015) recA 2121351..2122496 (-) 1146 WP_003038330.1 recombinase RecA Machinery gene
  SANR_RS10375 (SANR_2016) cinA 2122544..2123812 (-) 1269 WP_003038347.1 competence/damage-inducible protein A Machinery gene
  SANR_RS10380 (SANR_2017) - 2124453..2124824 (+) 372 WP_020999878.1 EamA family transporter -
  SANR_RS10385 (SANR_2018) - 2124933..2125505 (-) 573 WP_003038379.1 DNA-3-methyladenine glycosylase I -
  SANR_RS10390 (SANR_2019) ruvA 2125516..2126106 (-) 591 WP_003038332.1 Holliday junction branch migration protein RuvA -
  SANR_RS10395 - 2126205..2126543 (+) 339 WP_003038373.1 hypothetical protein -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45465.12 Da        Isoelectric Point: 6.6664

>NTDB_id=61695 SANR_RS10375 WP_003038347.1 2122544..2123812(-) (cinA) [Streptococcus anginosus C238]
MKAEIIAVGTEILTGQIVNTNARFLSEKLASLGVDVYFQTAVGDNEARLLSILEIARNRSNLVILTGGLGPTEDDLTKQT
LAKFLNRRLVFDRMATEKLDRFFASRPDYARTPNNERQAQIVEGSTPLQNETGLAVGGVIGVGGVTYVVLPGPPSELKPM
VNNELVPLLATGQKLYSRVLRFFGIGESQLVTLLGDLIDAQIDPTIAPYAKTGEVTLRLSTKAGSQKEADVKFAHLEKKI
LAVQTFEKQHLADLFYAYGDDSSLGQTAFELLIRAGKTVTAAESLTAGLFQATLANFAGASNVFSGGFVTYSMEEKSRML
GIPLADLEKHGVVSAFTAEKMAEQARKLTASDYAVSLTGVAGPDSLEGHPAGTVYIGLATTEDVQSIKVNIAGRSRTDVR
KIAVLHAFNLLRKTLLKNENML

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=61695 SANR_RS10375 WP_003038347.1 2122544..2123812(-) (cinA) [Streptococcus anginosus C238]
ATGAAAGCAGAAATTATTGCTGTGGGTACTGAAATTCTGACAGGTCAGATTGTCAATACAAATGCCCGATTTTTATCGGA
AAAATTAGCGAGTCTGGGTGTAGATGTGTATTTCCAAACAGCGGTTGGAGATAATGAAGCTCGTCTGTTATCCATTTTAG
AAATTGCTCGAAATCGTAGTAATTTGGTCATCTTAACTGGAGGATTAGGCCCAACAGAAGATGACTTGACTAAGCAGACT
TTGGCAAAATTCTTAAATCGTAGGTTGGTATTTGACCGAATGGCTACGGAGAAATTGGACCGCTTTTTCGCAAGTCGACC
GGATTATGCTCGAACACCAAACAATGAGCGGCAAGCTCAGATAGTGGAAGGCTCGACTCCTCTCCAAAACGAAACCGGAC
TTGCGGTGGGAGGCGTGATTGGAGTCGGCGGCGTGACTTATGTTGTTCTCCCCGGACCGCCTAGTGAATTAAAGCCTATG
GTAAATAATGAGCTAGTTCCGCTTTTAGCGACTGGTCAAAAATTGTATTCAAGAGTCTTGCGATTCTTTGGTATCGGTGA
AAGTCAATTAGTAACTCTTTTAGGAGATTTAATTGATGCTCAGATCGATCCGACCATTGCTCCTTATGCTAAGACGGGAG
AGGTGACATTGCGATTGTCCACAAAGGCTGGCAGTCAAAAGGAAGCAGATGTTAAGTTTGCTCATTTAGAAAAGAAAATT
TTGGCAGTACAGACTTTTGAGAAACAACATTTAGCAGACCTTTTCTACGCTTATGGAGATGATAGTTCTCTGGGACAAAC
AGCTTTTGAACTGCTGATAAGAGCAGGAAAGACCGTCACAGCAGCTGAAAGTTTGACTGCAGGACTCTTTCAAGCAACTT
TGGCAAACTTTGCTGGAGCCTCCAATGTTTTTAGTGGTGGCTTTGTTACCTACAGTATGGAGGAAAAGAGCCGAATGCTG
GGCATTCCCTTGGCAGACTTAGAAAAGCATGGGGTAGTTTCAGCTTTTACAGCGGAGAAAATGGCTGAGCAGGCAAGAAA
ATTGACCGCTAGTGACTATGCGGTGAGCTTGACAGGTGTGGCAGGTCCAGACAGCTTAGAAGGACATCCAGCAGGGACAG
TTTATATCGGCTTAGCAACTACAGAGGATGTTCAGTCTATTAAGGTTAATATTGCGGGTCGCAGTCGGACAGATGTACGT
AAAATAGCCGTTCTGCATGCTTTCAATCTGCTACGAAAAACTTTATTAAAAAACGAAAATATGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0S7M7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

76.077

99.052

0.754
  cinA Streptococcus pneumoniae TIGR4

75.359

99.052

0.746
  cinA Streptococcus pneumoniae Rx1

75.359

99.052

0.746
  cinA Streptococcus pneumoniae R6

75.359

99.052

0.746
  cinA Streptococcus mitis NCTC 12261

75.12

99.052

0.744
  cinA Streptococcus pneumoniae D39

75.12

99.052

0.744
  cinA Streptococcus mutans UA159

72.104

100

0.723
  cinA Streptococcus suis isolate S10

55.048

98.578

0.543
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

99.052

0.45

Multiple sequence alignment