Detailed information NTG0061692

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SANR_RS10010
• Genome accession: NC_022239
• Coordinates: 2063374..2065803 (-)
• Length: 809 a.a.
• NCBI ID: WP_003036608.1
• Uniprot ID: -
• Organism: Streptococcus anginosus C238
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 2058374..2070803

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SANR_RS09985 (SANR_1941)	-	2058655..2059473 (+)	819	WP_003036522.1	hypothetical protein	-
SANR_RS09990 (SANR_1942)	-	2059491..2060762 (+)	1272	Protein_1966	toxic anion resistance protein	-
SANR_RS09995 (SANR_1943)	hslO	2060983..2061855 (+)	873	WP_003036595.1	Hsp33 family molecular chaperone HslO	-
SANR_RS10000 (SANR_1944)	dusB	2061842..2062813 (+)	972	WP_003036548.1	tRNA dihydrouridine synthase DusB	-
SANR_RS10005 (SANR_1945)	-	2062887..2063327 (-)	441	WP_003036494.1	GNAT family N-acetyltransferase	-
SANR_RS10010 (SANR_1946)	clpC	2063374..2065803 (-)	2430	WP_003036608.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SANR_RS10015 (SANR_1947)	-	2065807..2066268 (-)	462	WP_003036579.1	CtsR family transcriptional regulator	-
SANR_RS10020 (SANR_1948)	-	2066527..2066877 (+)	351	WP_003036598.1	hypothetical protein	-
SANR_RS10025 (SANR_1949)	tsf	2066964..2068007 (-)	1044	WP_003026508.1	translation elongation factor Ts	-
SANR_RS10030 (SANR_1950)	rpsB	2068090..2068872 (-)	783	WP_003036542.1	30S ribosomal protein S2	-
SANR_RS10035 (SANR_1951)	comR/comR2	2069105..2069578 (-)	474	WP_020999414.1	sigma-70 family RNA polymerase sigma factor	Regulator
SANR_RS10040 (SANR_1952)	rplQ	2070005..2070391 (-)	387	WP_003026513.1	50S ribosomal protein L17	-

Sequence

Protein

• Length: 809 a.a.
• Molecular weight: 89896.32 Da
• Isoelectric Point: 6.6032

>NTDB_id=61692 SANR_RS10010 WP_003036608.1 2063374..2065803(-) (clpC) [Streptococcus anginosus C238]
MKYSKALTESIESAQLLASHFETDYLESWQLLIAMANNPYSVAGSVLNDYPLEIDDFEKAAFHITGKIYQQEGSFTIWPF
SHRMKVLFLTAERIAEAVHAKNLGTEHVLLAMLFDRGSLAARLLEFTGFSYEDKEGVLRMTDLRKNLEHKASWGKEDIKA
IRHLNKNIAAAKQTMANMMGMPPSTSGGLEDYTRDLTEMARAGLLEPVVGRDKEISRMLQILSRKTKNNPVLVGDAGVGK
TALALGLAQRVAAGQVPNELAKMRVLELDLMNVVAGTRFRGDFEERMNNIINDIEADGHVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKYIEKDAALSRRFAKITIEEPTVADSIAILQGLKKSYEEHHKVVITDSAIET
AVKYAHRYLTSKHLPDSAIDLLDEAAATVQNKGPQNHVKAELSAADEALMAGDWKKVGALLEKESQPIVYKLKVKDEDIL
ATLSGLSGIPVQKLTQTDAKKYLHLEKELHKRVIGQNEAISAISRAIRRNQSGIRTSKRPIGSFMFLGPTGVGKTELAKA
LAEVLFDDETALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
VLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDVRFDHENMEKRMMEELKKAYRPEFINRIDEKVVFHSLTSE
DMQEVVKIMVQPLISSLAEKGIKLKFQPSALKLLAQEGYDPEMGARPLRRILQTRVEDHLSELLLAGELKTGQSLKVGVK
AGKLKFEVL

Nucleotide

• Length: 2430 bp

>NTDB_id=61692 SANR_RS10010 WP_003036608.1 2063374..2065803(-) (clpC) [Streptococcus anginosus C238]
ATGAAATATTCAAAAGCTTTGACAGAAAGTATTGAGTCGGCACAACTGTTAGCGAGTCATTTTGAAACGGATTATTTGGA
GTCTTGGCAGCTGTTGATTGCTATGGCAAATAATCCTTATAGTGTTGCTGGTTCAGTTTTAAATGATTACCCACTTGAAA
TTGATGATTTTGAGAAAGCAGCCTTTCATATCACAGGAAAGATTTATCAACAAGAGGGAAGCTTTACCATTTGGCCATTT
TCTCATCGTATGAAAGTGTTGTTTTTAACAGCTGAGCGAATTGCAGAGGCTGTGCATGCTAAGAATCTTGGGACAGAGCA
TGTGTTGTTAGCTATGCTGTTTGACCGAGGAAGTTTGGCGGCACGTCTCCTTGAATTTACAGGCTTTAGCTATGAGGATA
AAGAAGGCGTTTTACGTATGACCGATCTTCGGAAAAACTTAGAGCATAAGGCTAGCTGGGGTAAAGAAGATATAAAAGCT
ATTCGCCACTTAAATAAAAATATTGCTGCAGCGAAACAAACGATGGCCAATATGATGGGGATGCCTCCTTCTACTAGTGG
CGGACTAGAAGATTATACCCGTGATTTAACCGAAATGGCTCGTGCTGGTCTTTTAGAACCGGTCGTTGGGCGTGATAAAG
AGATTTCTCGCATGCTTCAGATTTTAAGTCGCAAGACGAAAAATAATCCAGTGTTGGTAGGAGATGCAGGAGTTGGGAAG
ACAGCATTAGCCCTTGGTTTGGCGCAACGTGTGGCAGCTGGTCAAGTTCCAAATGAGCTTGCAAAGATGAGAGTTTTAGA
GCTAGATTTAATGAATGTGGTGGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGGATGAACAATATTATCAATGATA
TTGAAGCAGATGGACATGTCATTCTTTTCATTGATGAGCTTCATACTATTATGGGGTCGGGTAGCGGGATTGACTCGACA
TTAGATGCAGCGAACATTCTCAAGCCAGCTTTAGCTAGAGGGACGCTCAGAACGGTCGGCGCAACGACACAAGAAGAGTA
CCAGAAATATATTGAAAAGGACGCAGCTCTTTCACGGAGATTTGCCAAGATTACTATTGAAGAGCCGACGGTAGCTGATA
GTATTGCGATTTTACAGGGGCTCAAGAAAAGTTATGAAGAACACCACAAAGTGGTGATTACAGATTCAGCGATTGAGACA
GCTGTTAAGTATGCTCATCGTTATCTAACAAGCAAACACCTACCTGACTCGGCGATTGATTTGCTAGATGAAGCTGCTGC
AACGGTACAAAATAAAGGTCCACAAAATCATGTGAAAGCAGAATTGAGTGCAGCAGACGAGGCTTTAATGGCAGGCGATT
GGAAAAAGGTTGGCGCTTTGTTGGAGAAAGAAAGTCAGCCAATTGTCTACAAACTAAAGGTTAAAGACGAGGATATTTTG
GCAACACTCAGCGGTTTATCGGGCATTCCTGTGCAAAAGTTGACGCAAACAGATGCGAAGAAATACCTTCATTTAGAAAA
GGAACTTCACAAACGGGTCATTGGGCAAAATGAAGCAATTTCTGCTATCAGTCGAGCGATTCGGCGCAATCAATCCGGCA
TCCGCACCAGCAAACGTCCCATCGGCTCCTTTATGTTCTTAGGGCCAACCGGGGTCGGAAAAACTGAGCTAGCTAAGGCT
TTGGCAGAAGTTCTCTTTGATGACGAAACGGCACTGATTCGTTTTGATATGAGTGAATACATGGAAAAATTTGCTGCCAG
TCGCCTTAATGGAGCGCCTCCAGGTTATGTTGGTTATGAAGAAGGGGGCGAATTGACTGAAAAAGTTCGCAATCGTCCGT
ACTCTGTGCTCCTCTTTGATGAGGTAGAAAAAGCTCATCCTGATATTTTCAATGTGCTTCTCCAAGTCTTAGATGACGGG
GTGCTGACAGACAGCAAGGGGCGTAAGGTGGATTTTTCCAATACCATTATCATTATGACCAGCAATCTTGGTGCGACAAG
TTTACGGGACGACAAGACGGTTGGGTTCGGAGCAAGAGATGTTCGTTTTGATCATGAAAATATGGAAAAACGAATGATGG
AAGAGCTAAAGAAAGCTTATCGTCCAGAATTTATTAACCGAATTGATGAAAAGGTTGTTTTTCACAGTTTGACTAGCGAA
GACATGCAGGAAGTAGTGAAAATTATGGTGCAACCGCTCATTTCTAGTCTTGCAGAAAAAGGAATTAAACTCAAATTCCA
GCCGAGTGCTTTGAAGCTTCTAGCTCAAGAGGGCTATGATCCTGAAATGGGAGCTCGTCCATTGCGTCGAATTCTACAAA
CTCGGGTGGAAGACCATTTATCAGAATTACTTTTAGCAGGTGAGCTAAAAACGGGACAAAGCTTAAAAGTCGGTGTCAAG
GCTGGAAAATTGAAGTTTGAAGTGCTCTGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (717-797)

• AAA domain (Cdc48 subfamily) (AAA_2) (539-710)

• ATPase family associated with various cellular activities (AAA) (AAA) (231-350)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-60)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (91-130)

• AAA lid domain (AAA_lid_9) (371-445)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae TIGR4	77.559	100	0.778
clpC	Streptococcus pneumoniae Rx1	77.559	100	0.778
clpC	Streptococcus pneumoniae D39	77.559	100	0.778
clpC	Streptococcus mutans UA159	66.871	100	0.674
clpC	Streptococcus thermophilus LMG 18311	66.095	100	0.667
clpC	Streptococcus thermophilus LMD-9	65.973	100	0.666
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50	100	0.513
clpC	Bacillus subtilis subsp. subtilis str. 168	45.33	99.258	0.45
clpE	Streptococcus mutans UA159	47.106	76.885	0.362