Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NR349_RS09230 Genome accession   NZ_CP102380
Coordinates   1870376..1871032 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain BM28     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1865376..1876032
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NR349_RS09200 (NR349_09200) yecA 1866627..1867292 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  NR349_RS09220 (NR349_09220) pgsA 1867942..1868490 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NR349_RS09225 (NR349_09225) uvrC 1868547..1870379 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NR349_RS09230 (NR349_09230) letA 1870376..1871032 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NR349_RS21970 - 1871174..1871245 (+) 72 Protein_1811 transcriptional regulator -
  NR349_RS09235 (NR349_09235) yecU 1871328..1871504 (+) 177 WP_000590347.1 protein YecU -
  NR349_RS09240 (NR349_09240) yecF 1871491..1871715 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  NR349_RS09245 (NR349_09245) sdiA 1871783..1872505 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  NR349_RS09250 (NR349_09250) tcyN 1872735..1873487 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NR349_RS09255 (NR349_09255) tcyL 1873484..1874152 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  NR349_RS09260 (NR349_09260) dcyD 1874167..1875153 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=616366 NR349_RS09230 WP_000611335.1 1870376..1871032(-) (letA) [Escherichia coli strain BM28]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=616366 NR349_RS09230 WP_000611335.1 1870376..1871032(-) (letA) [Escherichia coli strain BM28]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486