Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   SCI_RS09945 Genome accession   NC_022238
Coordinates   1986694..1988007 (-) Length   437 a.a.
NCBI ID   WP_020998131.1    Uniprot ID   -
Organism   Streptococcus constellatus subsp. pharyngis C1050     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1981694..1993007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCI_RS09925 (SCI_1934) - 1983046..1985625 (+) 2580 WP_020998130.1 YfhO family protein -
  SCI_RS09940 (SCI_1937) comE 1985945..1986694 (-) 750 WP_003071650.1 competence system response regulator transcription factor ComE Regulator
  SCI_RS09945 (SCI_1938) comD/comD1 1986694..1988007 (-) 1314 WP_020998131.1 GHKL domain-containing protein Regulator
  SCI_RS10430 (SCI_1939) - 1988027..1988173 (-) 147 WP_006268843.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SCI_RS09960 (SCI_1941) rlmH 1988456..1988935 (-) 480 WP_006268880.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SCI_RS09965 (SCI_1942) htrA 1989140..1990330 (+) 1191 WP_006270334.1 S1C family serine protease Regulator
  SCI_RS09970 (SCI_1943) spo0J 1990385..1991152 (+) 768 WP_003071657.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 51588.22 Da        Isoelectric Point: 7.4636

>NTDB_id=61631 SCI_RS09945 WP_020998131.1 1986694..1988007(-) (comD/comD1) [Streptococcus constellatus subsp. pharyngis C1050]
MKIEFIHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFLTDFTTIIHYSVRYIMFFIQPLFFYLYFFKVKKHL
SVFLALFLSLAVSSSETFFSVIISSVTGDEFVDRYWGLFYIFINIISLIFILKTIDYFKFNFKYFKKVDFKDKIVQLNFY
LLFIHLLLNVSHWLSNMKNLNSFSSMIATICFLMFMSILFYLQSIREKYEKEEQIKQKEQEQLQLQKYTDEIVNLYNEIR
GFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKARDYNIELTFEV
KDFVKPLPIKLLDLVRMTSVLLNNAIEGAAESYQKTMNVSLVDLDTETILVIQNSRKKRQLDLEMIYQTDFSTKGEGRGL
GLSNIKEIINNYEGIILDTNIEDEYFTQVMRVRKEGL

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=61631 SCI_RS09945 WP_020998131.1 1986694..1988007(-) (comD/comD1) [Streptococcus constellatus subsp. pharyngis C1050]
GTGAAAATAGAATTTATACATTGGATTATATTCTCAATTATAGAAGCTGTTTCTGTTGTATATTGTTATAAGAAGATAAG
TAGAGTGAATAAAGTGAATATTCACTTTACTTTATTATGTTTAGGAATTGTATTTTTGACTGATTTTACTACAATAATAC
ATTATTCGGTTAGATATATAATGTTTTTTATTCAACCATTATTTTTTTATTTATATTTTTTTAAAGTAAAAAAACATCTT
TCTGTATTTTTAGCACTATTTTTATCTTTAGCTGTGTCAAGTTCTGAAACCTTCTTTTCAGTCATTATTTCTTCTGTCAC
AGGTGATGAGTTTGTTGATAGATACTGGGGATTGTTCTATATTTTTATCAATATTATTTCTTTAATTTTTATTTTAAAAA
CTATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGTTGATTTCAAAGATAAGATTGTACAATTAAATTTTTAT
CTATTATTTATTCATCTTTTATTAAATGTATCGCATTGGCTTAGTAACATGAAAAATTTAAATAGTTTTTCTAGTATGAT
TGCTACAATTTGCTTTTTAATGTTTATGTCAATTTTATTCTACTTACAATCTATTCGCGAAAAATATGAAAAAGAAGAAC
AAATTAAGCAAAAAGAACAGGAACAACTGCAATTACAAAAATATACAGATGAAATTGTTAATCTGTATAATGAAATTCGA
GGTTTTCGTCATGATTATGGTGGGATGTTGGCAAGTTTTCAATCAGCTATTCATACAGGTGATATAAAAGAAGTGGAGCG
AATCTATCAGGAGGTTCTCGTAAATGCTAATTTACAGCTTCGTTCTGATAAATATACGTATTTTGATTTAAATAATGTTG
GAGATTCAGCACTTAGAAGTGTTATGACGCAAACATTATTTAAGGCACGAGATTACAATATAGAATTAACATTTGAAGTA
AAAGATTTTGTCAAGCCTTTACCGATTAAATTATTAGATCTAGTTAGAATGACAAGTGTTCTTTTAAATAATGCCATAGA
AGGAGCAGCAGAAAGTTATCAAAAAACAATGAATGTTTCTTTGGTAGATTTGGATACAGAAACTATCTTAGTCATTCAAA
ATTCACGTAAAAAAAGACAACTAGACTTAGAAATGATTTATCAAACCGATTTTTCAACAAAGGGCGAGGGACGAGGTTTA
GGTTTAAGCAATATCAAAGAAATTATTAATAACTATGAAGGAATTATTCTTGATACAAACATTGAGGATGAATATTTTAC
ACAAGTAATGAGAGTAAGGAAAGAAGGTCTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(330-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

54.795

100

0.549
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.299

100

0.549
  comD Streptococcus mitis SK321

46.939

89.703

0.421
  comD/comD2 Streptococcus pneumoniae TIGR4

48.138

86.041

0.414
  comD Streptococcus mitis NCTC 12261

48.138

86.041

0.414
  comD/comD1 Streptococcus pneumoniae Rx1

47.606

86.041

0.41
  comD/comD1 Streptococcus pneumoniae D39

47.606

86.041

0.41
  comD/comD1 Streptococcus pneumoniae R6

47.606

86.041

0.41

Multiple sequence alignment