Detailed information NTG0616146

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: NRF20_RS25395
• Genome accession: NZ_CP102361
• Coordinates: 5547613..5548737 (-)
• Length: 374 a.a.
• NCBI ID: WP_114245192.1
• Uniprot ID: A0ABY9IUC4
• Organism: Streptomyces sp. R-74717
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5542613..5553737

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NRF20_RS25370 (NRF20_25330)	-	5543255..5543995 (-)	741	WP_398628062.1	hypothetical protein	-
NRF20_RS25375 (NRF20_25335)	-	5543983..5544633 (-)	651	WP_266360524.1	SigE family RNA polymerase sigma factor	-
NRF20_RS25380 (NRF20_25340)	-	5544809..5545711 (-)	903	WP_398628061.1	A/G-specific adenine glycosylase	-
NRF20_RS25385 (NRF20_25345)	-	5545856..5546500 (-)	645	WP_398628060.1	phosphatase PAP2 family protein	-
NRF20_RS25390 (NRF20_25350)	-	5546674..5547504 (+)	831	WP_398628059.1	hypothetical protein	-
NRF20_RS25395 (NRF20_25355)	disA	5547613..5548737 (-)	1125	WP_114245192.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
NRF20_RS25400 (NRF20_25360)	radA/sms	5548818..5550230 (-)	1413	WP_398628058.1	DNA repair protein RadA	Machinery gene
NRF20_RS25405 (NRF20_25365)	-	5550471..5552360 (+)	1890	WP_413753315.1	BACON domain-containing protein	-
NRF20_RS25410 (NRF20_25370)	-	5552466..5553317 (-)	852	WP_398628056.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40372.27 Da
• Isoelectric Point: 4.9352

>NTDB_id=616146 NRF20_RS25395 WP_114245192.1 5547613..5548737(-) (disA) [Streptomyces sp. R-74717]
MAASDRAASPGKSGQGTGNEALMRASLTAVAPGMALRDGLERILRGNTGGLIVLGMDRTVESMCTGGFVLDVEFTATRLR
ELAKLDGALILDKDMTKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCNFPVVSVSQSMHLIALYVDGERRVLEESAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALTELDALSHTELLELPVVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=616146 NRF20_RS25395 WP_114245192.1 5547613..5548737(-) (disA) [Streptomyces sp. R-74717]
GTGGCAGCCAGCGACCGGGCAGCATCGCCCGGAAAGTCCGGCCAAGGCACCGGTAACGAGGCGCTGATGCGCGCCTCGTT
GACCGCCGTCGCGCCCGGAATGGCCCTGCGGGACGGCCTGGAGCGCATCCTCCGTGGCAACACCGGCGGGCTGATCGTCC
TGGGCATGGACAGAACCGTCGAGTCGATGTGCACCGGCGGATTCGTGCTGGACGTGGAGTTCACCGCGACGCGTCTGCGC
GAGCTGGCCAAGCTCGACGGGGCGCTGATCCTCGACAAGGACATGACCAAGATCCTGCGGGCCGGTGTGCAGCTGGTCCC
GGACGCCTCCATCCCCACCGAGGAGACCGGCACCCGCCACCGCACGGCGGACCGGGTCTCCAAGCAGTGCAACTTCCCGG
TCGTCTCGGTCTCGCAGTCGATGCACCTCATCGCGCTGTACGTGGACGGGGAGCGCCGGGTCCTGGAGGAGTCCGCCGCG
ATCCTCTCCCGCGCCAATCAGGCACTCGCCACCCTGGAGCGGTACAAGCTCCGCCTCGACGAGGTCGCGGGCACCCTCTC
GGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGATGTGACGGCCGTCGCACAGCGGCTGGAGATGGTCCGCCGGATCG
CGACCGAGATCGCGGAGTACGTGGTGGAGCTGGGCACCGACGGCCGGCTCCTCTCGCTCCAGCTGGACGAGTTGATCGCC
GGCGTCGAGCCGGAGCGTGAGCTGGTCGTGCGCGACTATGTGCCGGAGCCGACCGCGAAGCGGTCCCGTACGGTCGCCGA
AGCACTGACCGAACTCGACGCGCTCTCCCACACCGAACTGCTCGAACTCCCCGTCGTGGCAAGGGCGCTGGGGTACAGCG
GCTCGCCGGAGACGCTGGATTCGGCGGTCTCGCCGCGCGGCTTCCGGCTGCTGGCGAAGGTGCCGCGGCTGCCCGGGGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGCCTGCAGAAGCTCCTTGCCGCCAGCGTGGACGACCTCCAGACGGTGGA
CGGGGTCGGCGAGGCGCGGGCGAGGAGCGTGCGCGAGGGGTTGTCGCGACTGGCCGAGTCGTCGATTCTCGAGCGGTACG
TGTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.152	96.524	0.436