Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SCI_RS07740 Genome accession   NC_022238
Coordinates   1561866..1562555 (-) Length   229 a.a.
NCBI ID   WP_020998001.1    Uniprot ID   U2XYT2
Organism   Streptococcus constellatus subsp. pharyngis C1050     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1556866..1567555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCI_RS07725 (SCI_1513) nrdR 1557978..1558451 (-) 474 WP_003068126.1 transcriptional regulator NrdR -
  SCI_RS07730 (SCI_1514) - 1558634..1559449 (-) 816 WP_020997999.1 endonuclease/exonuclease/phosphatase family protein -
  SCI_RS07735 (SCI_1515) - 1559466..1561655 (-) 2190 WP_020998000.1 PTS transporter subunit IIBC -
  SCI_RS07740 (SCI_1516) covR 1561866..1562555 (-) 690 WP_020998001.1 response regulator transcription factor Regulator
  SCI_RS07745 (SCI_1517) gndA 1562564..1563988 (-) 1425 WP_020999403.1 NADP-dependent phosphogluconate dehydrogenase -
  SCI_RS07750 (SCI_1518) - 1564080..1564616 (-) 537 WP_006268073.1 DUF177 domain-containing protein -
  SCI_RS07755 (SCI_1519) - 1564804..1566054 (+) 1251 WP_006268318.1 hypothetical protein -
  SCI_RS07760 (SCI_1520) htpX 1566123..1567019 (-) 897 WP_006268546.1 zinc metalloprotease HtpX -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26587.66 Da        Isoelectric Point: 6.1345

>NTDB_id=61606 SCI_RS07740 WP_020998001.1 1561866..1562555(-) (covR) [Streptococcus constellatus subsp. pharyngis C1050]
MGKRILLVENEKKLAQFISLELQNEGYRVDLLETGKDALTSARANQYDLFLLNFMLEDMTGTEFAEQLSLIKPASVIIVL
DNRDIILKYTEEIQRFAVSYMIEPFIVMDLVEKISAIFRGRDFIDHHCSQMKVSTSYRNLRIDVQNHTVYRGNEIISLTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKLDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=61606 SCI_RS07740 WP_020998001.1 1561866..1562555(-) (covR) [Streptococcus constellatus subsp. pharyngis C1050]
ATGGGGAAGCGGATTTTATTAGTTGAGAATGAAAAAAAATTAGCACAATTTATTAGCTTAGAGTTGCAAAATGAAGGTTA
TCGAGTGGATCTTCTTGAAACGGGAAAAGATGCTTTAACATCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGAAGATATGACAGGAACGGAGTTTGCTGAGCAATTAAGTTTGATAAAGCCTGCTTCAGTCATTATTGTATTG
GATAATCGTGATATTATTTTAAAATATACTGAGGAAATCCAACGTTTTGCTGTTAGTTATATGATAGAGCCTTTCATTGT
GATGGACTTGGTCGAAAAAATTTCTGCTATTTTTCGAGGGCGTGATTTTATCGATCATCATTGTAGTCAGATGAAAGTTT
CAACATCTTATCGGAATCTTCGCATTGACGTGCAAAATCATACTGTATATCGAGGGAATGAAATAATTTCTTTGACTAGA
AGAGAGTATGATTTGTTAGCAACGCTGATGGGCAGTCATCAGGCTTTAAGCCGTGAACAGCTGTTAGAGCGCGTTTGGAA
ATACGAAGGAGCAGTCGAAACAAATGTTGTTGATGTCTATATTCGTTATCTTCGTAGTAAACTTGATATAGCAGGGCAGA
AAAGTTACATAAAAACCGTGCGTGGTGTTGGCTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U2XYT2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.175

99.563

0.45

Multiple sequence alignment