Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NQZ80_RS10275 Genome accession   NZ_CP102244
Coordinates   2148226..2148882 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O7:H15 strain ST70     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2143226..2153882
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ80_RS10245 (NQZ80_10245) dcyD 2144105..2145091 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NQZ80_RS10250 (NQZ80_10250) tcyL 2145106..2145774 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NQZ80_RS10255 (NQZ80_10255) tcyN 2145771..2146523 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NQZ80_RS10260 (NQZ80_10260) sdiA 2146753..2147475 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  NQZ80_RS10265 (NQZ80_10265) yecF 2147543..2147767 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NQZ80_RS10270 (NQZ80_10270) yecU 2147754..2147930 (-) 177 WP_000590347.1 protein YecU -
  NQZ80_RS10275 (NQZ80_10275) letA 2148226..2148882 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NQZ80_RS10280 (NQZ80_10280) uvrC 2148879..2150711 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NQZ80_RS10285 (NQZ80_10285) pgsA 2150768..2151316 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NQZ80_RS10305 (NQZ80_10305) yecA 2151966..2152631 (+) 666 WP_000847874.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=615963 NQZ80_RS10275 WP_000611328.1 2148226..2148882(+) (letA) [Escherichia coli O7:H15 strain ST70]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=615963 NQZ80_RS10275 WP_000611328.1 2148226..2148882(+) (letA) [Escherichia coli O7:H15 strain ST70]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482