Detailed information NTG0061569

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: SCI_RS00075
• Genome accession: NC_022238
• Coordinates: 15959..16441 (+)
• Length: 160 a.a.
• NCBI ID: WP_006267672.1
• Uniprot ID: A0A380L5Q1
• Organism: Streptococcus constellatus subsp. pharyngis C1050
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 10959..21441

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCI_RS00055 (SCI_0012)	tilS	11155..12432 (+)	1278	WP_020997509.1	tRNA lysidine(34) synthetase TilS	-
SCI_RS00060 (SCI_0013)	hpt	12438..12980 (+)	543	WP_020997510.1	hypoxanthine phosphoribosyltransferase	-
SCI_RS00065 (SCI_0014)	ftsH	13001..14971 (+)	1971	WP_006268871.1	ATP-dependent zinc metalloprotease FtsH	-
SCI_RS10805 (SCI_0015)	-	15196..15363 (+)	168	Protein_14	IS200/IS605 family transposase	-
SCI_RS10045	rplQ	15360..15527 (+)	168	Protein_15	50S ribosomal protein L17	-
SCI_RS00075 (SCI_0016)	comR/comR2	15959..16441 (+)	483	WP_006267672.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 160 a.a.
• Molecular weight: 19855.70 Da
• Isoelectric Point: 7.9710

>NTDB_id=61569 SCI_RS00075 WP_006267672.1 15959..16441(+) (comR/comR2) [Streptococcus constellatus subsp. pharyngis C1050]
MDFKELYDKVRGIVLKCRREYYVHLWELSDWDQEGMLVLYELVSRYPQLVESESRLYVYYKTKFRNHIKDILRKQESQKR
KLDRQVYEEVSEIGHKLSLKELYLDELVILRDQLKSYQKQLSPEKQEQYERLLADERFQGRQAMLRELRTYLQDYDERKS

Nucleotide

• Length: 483 bp

>NTDB_id=61569 SCI_RS00075 WP_006267672.1 15959..16441(+) (comR/comR2) [Streptococcus constellatus subsp. pharyngis C1050]
ATGGACTTCAAGGAATTGTATGACAAAGTGAGAGGGATCGTACTGAAGTGTCGCCGGGAATATTATGTCCACCTGTGGGA
GTTAAGTGATTGGGACCAAGAAGGGATGCTGGTCTTATATGAGTTGGTGAGTCGCTATCCGCAACTGGTAGAGTCAGAAA
GTCGTCTCTATGTTTACTATAAGACCAAGTTCCGTAATCACATCAAGGACATCCTGCGCAAACAAGAAAGCCAAAAGCGC
AAACTAGACCGTCAAGTCTATGAGGAAGTGAGCGAGATAGGTCACAAGCTCAGCCTGAAAGAACTCTATTTGGATGAATT
GGTGATTCTCCGAGACCAACTAAAGAGCTATCAAAAACAGCTAAGTCCAGAGAAACAAGAACAGTATGAGCGCTTACTAG
CAGATGAACGGTTTCAAGGACGCCAAGCGATGCTTCGGGAGTTACGGACCTACTTACAAGATTACGATGAAAGAAAAAGC
TAG

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A380L5Q1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	61.392	98.75	0.606
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	61.392	98.75	0.606
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	56.41	97.5	0.55
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	55.128	97.5	0.537
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	55.128	97.5	0.537
comX/comX1	Streptococcus pneumoniae R6	55.556	95.625	0.531
comX/comX1	Streptococcus pneumoniae D39	55.556	95.625	0.531
comX/comX2	Streptococcus pneumoniae Rx1	55.556	95.625	0.531
comX/comX1	Streptococcus pneumoniae Rx1	55.556	95.625	0.531
comX/comX2	Streptococcus pneumoniae D39	55.556	95.625	0.531
comX/comX2	Streptococcus pneumoniae R6	55.556	95.625	0.531
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	54.487	97.5	0.531
comX/comX2	Streptococcus pneumoniae TIGR4	54.902	95.625	0.525
comX/comX1	Streptococcus pneumoniae TIGR4	54.902	95.625	0.525
comX/sigX	Streptococcus mutans UA159	50.318	98.125	0.494
comX/sigX	Streptococcus suis D9	46.452	96.875	0.45
comX/sigX	Streptococcus suis isolate S10	46.452	96.875	0.45
comX/sigX	Streptococcus suis P1/7	46.452	96.875	0.45
comX	Streptococcus salivarius SK126	43.506	96.25	0.419
comX/sigX	Streptococcus salivarius strain HSISS4	42.857	96.25	0.412
comX	Streptococcus thermophilus LMG 18311	42.857	96.25	0.412
comX	Streptococcus thermophilus LMD-9	42.857	96.25	0.412
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40.764	98.125	0.4
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40.764	98.125	0.4
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	40.764	98.125	0.4
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	40.764	98.125	0.4
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40.764	98.125	0.4
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40.764	98.125	0.4
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	39.744	97.5	0.388
comX	Streptococcus sobrinus strain NIDR 6715-7	37.419	96.875	0.362