Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SII_RS01710 Genome accession   NC_022237
Coordinates   331224..331913 (+) Length   229 a.a.
NCBI ID   WP_009569219.1    Uniprot ID   -
Organism   Streptococcus intermedius C270     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 326224..336913
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SII_RS01690 (SII_0331) htpX 326750..327646 (+) 897 WP_009569222.1 zinc metalloprotease HtpX -
  SII_RS01695 (SII_0332) - 327749..328975 (-) 1227 WP_020998337.1 hypothetical protein -
  SII_RS01700 (SII_0333) - 329163..329699 (+) 537 WP_020998338.1 DUF177 domain-containing protein -
  SII_RS01705 (SII_0334) gndA 329791..331215 (+) 1425 WP_006268166.1 NADP-dependent phosphogluconate dehydrogenase -
  SII_RS01710 (SII_0335) covR 331224..331913 (+) 690 WP_009569219.1 DNA-binding response regulator Regulator
  SII_RS01715 (SII_0336) - 332214..332669 (+) 456 Protein_308 PTS glucose transporter subunit IIA -
  SII_RS01720 (SII_0337) - 332881..335070 (+) 2190 WP_020998340.1 PTS transporter subunit IIBC -
  SII_RS01725 (SII_0338) - 335088..335903 (+) 816 WP_020998341.1 endonuclease/exonuclease/phosphatase family protein -
  SII_RS01730 (SII_0339) - 335954..336397 (-) 444 WP_020998342.1 hypothetical protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26558.62 Da        Isoelectric Point: 6.6513

>NTDB_id=61511 SII_RS01710 WP_009569219.1 331224..331913(+) (covR) [Streptococcus intermedius C270]
MGKRILLVENEKKLAQFISLELQNEGYRVDLFETGKDALTSARANQYDLFLLNFMLEDMTGTEFAEQLSLIKPASVIIVL
DNRDIILKYTEEIQRFAVSYMIEPFIVMDLVGKISAIFRGRDFIDHHCSQMKVSTSYRNLRIDVQNHTVYRGNEIISLTR
REYDLLATLMGSHHALSREQLLERVWKYEGAVETNVVDVYIRYLRSKLDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=61511 SII_RS01710 WP_009569219.1 331224..331913(+) (covR) [Streptococcus intermedius C270]
ATGGGGAAGCGGATTTTATTAGTTGAGAATGAAAAAAAATTAGCACAATTTATTAGCTTAGAGTTGCAAAATGAAGGTTA
TCGAGTGGATCTTTTTGAAACGGGAAAAGATGCTTTAACATCTGCGAGAGCTAATCAATACGATTTATTCCTGTTAAATT
TTATGCTTGAAGATATGACAGGAACGGAGTTTGCTGAGCAATTGAGTTTGATAAAGCCTGCTTCAGTCATTATTGTATTG
GATAATCGTGATATTATTTTAAAATATACTGAGGAAATCCAACGTTTTGCTGTTAGTTATATGATAGAGCCTTTCATTGT
GATGGACTTGGTCGGAAAAATTTCTGCTATTTTTCGTGGGCGTGATTTTATTGATCATCATTGTAGTCAGATGAAAGTTT
CAACATCTTATCGGAATCTTCGCATTGACGTGCAAAATCATACTGTATATCGAGGGAATGAAATAATTTCTTTGACTAGA
AGAGAGTATGATTTGTTAGCAACGCTGATGGGCAGTCATCATGCTTTAAGCCGTGAACAGCTGTTAGAGCGCGTTTGGAA
ATACGAAGGAGCTGTTGAGACAAATGTTGTTGATGTCTATATTCGTTATCTTCGTAGTAAACTTGATATAGCAGGGCAGA
AAAGTTACATCAAAACTGTGCGTGGTGTTGGCTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-227)

Response regulator receiver domain (Response_reg)

(5-82)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.175

99.563

0.45

Multiple sequence alignment