Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   NQZ97_RS09495 Genome accession   NZ_CP102136
Coordinates   1941273..1941914 (-) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain M105052_S26     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1936273..1946914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ97_RS09470 (NQZ97_09470) comFA/cflA 1936426..1937718 (-) 1293 WP_170238431.1 DEAD/DEAH box helicase Machinery gene
  NQZ97_RS09475 (NQZ97_09475) - 1937775..1938407 (+) 633 WP_170238432.1 YigZ family protein -
  NQZ97_RS09480 (NQZ97_09480) cysK 1938497..1939423 (+) 927 WP_002937015.1 cysteine synthase A -
  NQZ97_RS09485 (NQZ97_09485) - 1939450..1939821 (-) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  NQZ97_RS09490 (NQZ97_09490) - 1939823..1941223 (-) 1401 WP_024377222.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  NQZ97_RS09495 (NQZ97_09495) vraR 1941273..1941914 (-) 642 WP_002937025.1 response regulator transcription factor Regulator
  NQZ97_RS09500 (NQZ97_09500) - 1941886..1942902 (-) 1017 WP_105130094.1 sensor histidine kinase -
  NQZ97_RS09505 (NQZ97_09505) liaF 1942899..1943558 (-) 660 WP_257110566.1 cell wall-active antibiotics response protein LiaF -
  NQZ97_RS09510 (NQZ97_09510) - 1944139..1945260 (-) 1122 WP_257110567.1 IS110 family transposase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=614920 NQZ97_RS09495 WP_002937025.1 1941273..1941914(-) (vraR) [Streptococcus suis strain M105052_S26]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=614920 NQZ97_RS09495 WP_002937025.1 1941273..1941914(-) (vraR) [Streptococcus suis strain M105052_S26]
ATGAATACGATTCGAGTGATGTTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCCGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGGGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413