Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   NQZ97_RS00405 Genome accession   NZ_CP102136
Coordinates   72222..74159 (+) Length   645 a.a.
NCBI ID   WP_043025667.1    Uniprot ID   -
Organism   Streptococcus suis strain M105052_S26     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 67222..79159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ97_RS00385 (NQZ97_00385) - 67359..67982 (+) 624 WP_044672706.1 HAD-IA family hydrolase -
  NQZ97_RS00390 (NQZ97_00390) comR 68053..68952 (+) 900 WP_004195451.1 helix-turn-helix domain-containing protein Regulator
  NQZ97_RS00395 (NQZ97_00395) - 69170..70390 (+) 1221 WP_256787687.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  NQZ97_RS00400 (NQZ97_00400) - 70581..72104 (+) 1524 WP_256787686.1 quinol oxidase -
  NQZ97_RS00405 (NQZ97_00405) hexB 72222..74159 (+) 1938 WP_043025667.1 DNA mismatch repair endonuclease MutL Machinery gene
  NQZ97_RS00410 (NQZ97_00410) ruvA 74198..74788 (+) 591 WP_043025669.1 Holliday junction branch migration protein RuvA Machinery gene
  NQZ97_RS00415 (NQZ97_00415) - 75393..75962 (+) 570 WP_043025096.1 DNA-3-methyladenine glycosylase I -
  NQZ97_RS00420 (NQZ97_00420) cinA 75999..77180 (+) 1182 WP_043025095.1 competence/damage-inducible protein A Machinery gene
  NQZ97_RS00425 (NQZ97_00425) recA 77232..78383 (+) 1152 WP_004195473.1 recombinase RecA Machinery gene
  NQZ97_RS00430 (NQZ97_00430) spx 78543..78941 (+) 399 WP_004195475.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72794.03 Da        Isoelectric Point: 5.2313

>NTDB_id=614848 NQZ97_RS00405 WP_043025667.1 72222..74159(+) (hexB) [Streptococcus suis strain M105052_S26]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASVSHMIIETATADSAHGLHLEAKGGIIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFALVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMAALRQVGVNLEEYGANQFILREHPIWMKEEEIGSGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=614848 NQZ97_RS00405 WP_043025667.1 72222..74159(+) (hexB) [Streptococcus suis strain M105052_S26]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTCAAAA
TGATTCAAATTACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAGTCAATCGGATTTGTTTCGTATTCGCACCCTAGGTTTTCGTGGAGAAGCTCTGCCTTCCATTGCTTCTGTTAG
TCATATGATCATTGAGACAGCTACGGCAGACTCTGCACACGGACTTCATTTGGAGGCCAAAGGTGGTATCATCGAGAAAG
AGGAGCCAGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCTTT
TGCCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTACGTTTCCTTGCCA
GAGTTGACTCGCGCCAACCGCAACTACATTTCCATTTTCATCAATGGTCGCTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTATGGCAGTAAGTTGATGGTAGGACGTTTTCCATTGGCAGTGATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGTACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGATGTTGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAAA
CCTACATCTGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGAAGATCAGGAGCATCCTAATCTAAGCGCAAAAGAATT
GGCAAAACTAGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAGATGCATGGGA
CGTATTTATTTGCGCAAGGTAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCAGCCCAACAGTTATTGGTGCCGTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTTGTCCACAAAATGGCTGCCCTTCGTCAAGTAGGTGTCAACTTAGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAGGAGATTGGGTCTGGCATTTATGAGATGTGCGACATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCTATCATGATGTCTTGTAAACGGTCGATCAAGGCCAATCA
TGCTCTGGATGATTACTCGGCGCGTGATTTACTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGTC
GCCCAGTCTTAGTACATTTTAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAAGAAAATCACACGAGTTTGCGA
GAGTTGGGGAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(447-589)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.308

100

0.729